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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN14
All Species:
27.27
Human Site:
Y256
Identified Species:
66.67
UniProt:
A8MX76
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MX76
NP_001138594.1
684
79568
Y256
G
L
V
E
G
H
A
Y
T
L
T
G
I
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096026
884
100839
Y409
G
L
V
E
G
H
A
Y
T
V
T
G
I
R
K
Dog
Lupus familis
XP_540141
564
63825
G164
K
R
L
D
L
C
Q
G
V
V
G
D
C
W
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6J756
714
82951
Y274
M
L
V
R
G
H
A
Y
A
V
T
G
L
E
D
Rat
Rattus norvegicus
Q78EJ9
703
79537
Y264
K
L
V
K
G
H
A
Y
S
V
T
G
V
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510440
733
83715
Y264
G
L
V
D
G
H
A
Y
T
L
T
G
I
R
K
Chicken
Gallus gallus
Q92177
810
93542
Y329
G
L
V
K
G
H
A
Y
S
V
T
A
V
E
E
Frog
Xenopus laevis
NP_001083713
699
79286
Y264
K
L
V
K
G
H
A
Y
S
V
T
A
A
E
E
Zebra Danio
Brachydanio rerio
NP_001035341
693
78760
Y265
G
L
V
E
M
H
A
Y
T
V
T
G
V
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT65
925
103795
R468
E
T
P
Q
G
L
I
R
G
H
A
Y
S
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
60.9
57.8
N.A.
36.5
37.7
N.A.
56.4
33.9
36.9
37.9
N.A.
27.2
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
66.4
63.2
N.A.
56.8
56.4
N.A.
70.8
50
56
57.4
N.A.
43.1
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
0
N.A.
53.3
53.3
N.A.
93.3
53.3
46.6
66.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
66.6
86.6
N.A.
100
86.6
73.3
86.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
80
0
10
0
10
20
10
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
10
0
0
30
0
0
0
0
0
0
0
0
0
40
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
50
0
0
0
80
0
0
10
10
0
10
60
0
0
0
% G
% His:
0
0
0
0
0
80
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
30
10
0
% I
% Lys:
30
0
0
30
0
0
0
0
0
0
0
0
0
0
30
% K
% Leu:
0
80
10
0
10
10
0
0
0
20
0
0
10
0
0
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
0
10
0
0
0
0
0
30
0
% R
% Ser:
0
0
0
0
0
0
0
0
30
0
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
40
0
80
0
0
10
10
% T
% Val:
0
0
80
0
0
0
0
0
10
70
0
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _