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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRXCR1
All Species:
22.73
Human Site:
S216
Identified Species:
55.56
UniProt:
A8MXD5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MXD5
NP_001073945.1
290
32294
S216
G
G
A
E
K
I
L
S
M
N
E
S
G
E
L
Chimpanzee
Pan troglodytes
XP_517170
290
32231
S216
G
G
A
E
K
I
L
S
M
N
E
S
G
E
L
Rhesus Macaque
Macaca mulatta
XP_001099443
290
32333
S216
G
G
A
E
K
I
L
S
M
N
E
S
G
E
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q50H32
290
32383
S216
G
G
A
E
K
I
L
S
M
N
E
S
G
E
L
Rat
Rattus norvegicus
XP_573590
290
32374
S216
G
G
A
E
K
I
L
S
M
N
E
S
G
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521481
287
31767
S210
G
G
A
E
K
I
L
S
M
N
E
S
G
E
L
Chicken
Gallus gallus
XP_001233963
311
34717
L237
G
G
A
E
K
I
L
L
M
N
E
S
G
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4S1
582
63351
R510
G
D
A
N
I
V
E
R
L
N
E
S
G
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195463
173
20146
R107
N
E
S
G
E
L
R
R
I
L
K
R
F
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLE8
390
43925
K307
G
G
V
E
E
I
K
K
L
N
E
N
G
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.2
N.A.
N.A.
92.4
91.7
N.A.
78.9
75.8
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
30.3
Protein Similarity:
100
99.3
99.3
N.A.
N.A.
95.1
94.8
N.A.
84.4
82.6
N.A.
N.A.
N.A.
32.8
N.A.
N.A.
42.4
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
80
20
0
10
0
0
0
90
0
0
100
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
90
80
0
10
0
0
0
0
0
0
0
0
90
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
80
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
70
0
10
10
0
0
10
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
70
10
20
10
0
0
0
0
90
% L
% Met:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
90
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
20
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
60
0
0
0
80
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _