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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 7.27
Human Site: Y196 Identified Species: 16
UniProt: A8MXE2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A8MXE2 XP_002342992.1 369 42761 Y196 N L P S L V D Y L L N L K E H
Chimpanzee Pan troglodytes Q9N295 297 34832 C146 I E W V H R F C P Q A A F V M
Rhesus Macaque Macaca mulatta XP_001096544 508 58060 Y335 N L P S L V D Y L L N L K E H
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BGY6 376 43895 L205 M P N L I E Y L Q G L E Q I G
Rat Rattus norvegicus Q99NB2 377 44112 L206 M P N L I E Y L Q G L E Q V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521088 377 44085 L206 M P N L V A Y L Q S L E Q I G
Chicken Gallus gallus XP_415409 368 42094 G195 V G I P S L A G Y L L S L T Q
Frog Xenopus laevis Q5HZL5 377 43616 Y206 H T P N L V S Y L K S L P I E
Zebra Danio Brachydanio rerio Q7T3S5 379 43582 L208 V P N L V H Y L Q E L K S Q N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95US5 322 37568 P171 N P N Q C S S P D F T F L V D
Sea Urchin Strong. purpuratus XP_001179708 291 33403 F140 G M K W V S Q F C P H A N Y V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.4 68.5 N.A. N.A. 29.7 29.1 N.A. 30.2 58.8 29.4 28.2 N.A. N.A. N.A. 25.4 27.9
Protein Similarity: 100 46.6 70.2 N.A. N.A. 49.4 48.2 N.A. 51.4 75.6 50.9 50.9 N.A. N.A. N.A. 43.9 44.9
P-Site Identity: 100 0 100 N.A. N.A. 0 0 N.A. 0 6.6 40 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 0 100 N.A. N.A. 13.3 13.3 N.A. 13.3 13.3 60 20 N.A. N.A. N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 0 0 10 19 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 10 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 19 0 10 0 0 0 0 0 10 % D
% Glu: 0 10 0 0 0 19 0 0 0 10 0 28 0 19 10 % E
% Phe: 0 0 0 0 0 0 10 10 0 10 0 10 10 0 0 % F
% Gly: 10 10 0 0 0 0 0 10 0 19 0 0 0 0 28 % G
% His: 10 0 0 0 10 10 0 0 0 0 10 0 0 0 19 % H
% Ile: 10 0 10 0 19 0 0 0 0 0 0 0 0 28 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 10 0 10 19 0 0 % K
% Leu: 0 19 0 37 28 10 0 37 28 28 46 28 19 0 0 % L
% Met: 28 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 28 0 46 10 0 0 0 0 0 0 19 0 10 0 10 % N
% Pro: 0 46 28 10 0 0 0 10 10 10 0 0 10 0 0 % P
% Gln: 0 0 0 10 0 0 10 0 37 10 0 0 28 10 10 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 19 10 19 19 0 0 10 10 10 10 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 10 0 0 10 0 % T
% Val: 19 0 0 10 28 28 0 0 0 0 0 0 0 28 10 % V
% Trp: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 37 28 10 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _