KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
18.79
Human Site:
Y238
Identified Species:
41.33
UniProt:
A8MXE2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A8MXE2
XP_002342992.1
369
42761
Y238
S
E
Y
P
E
K
Y
Y
P
D
Y
C
S
G
E
Chimpanzee
Pan troglodytes
Q9N295
297
34832
E188
T
G
F
L
K
L
N
E
F
P
I
R
Q
P
F
Rhesus Macaque
Macaca mulatta
XP_001096544
508
58060
Y377
S
E
Y
P
E
K
Y
Y
P
D
Y
C
S
G
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGY6
376
43895
Y247
E
M
Y
K
W
P
A
Y
P
D
Y
T
A
G
A
Rat
Rattus norvegicus
Q99NB2
377
44112
Y248
E
M
Y
K
W
P
A
Y
P
D
Y
T
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521088
377
44085
Y248
E
M
Y
H
W
P
A
Y
P
D
Y
T
A
G
A
Chicken
Gallus gallus
XP_415409
368
42094
Y237
H
Q
Y
P
E
E
F
Y
P
D
Y
C
D
R
R
Frog
Xenopus laevis
Q5HZL5
377
43616
Y248
E
M
Y
P
W
S
S
Y
P
D
Y
T
A
G
A
Zebra Danio
Brachydanio rerio
Q7T3S5
379
43582
Y250
D
M
Y
Q
W
S
S
Y
P
D
Y
T
A
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95US5
322
37568
R213
V
F
D
T
S
P
F
R
L
K
I
H
K
H
S
Sea Urchin
Strong. purpuratus
XP_001179708
291
33403
R182
F
V
S
C
I
V
I
R
A
K
P
N
R
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
68.5
N.A.
N.A.
29.7
29.1
N.A.
30.2
58.8
29.4
28.2
N.A.
N.A.
N.A.
25.4
27.9
Protein Similarity:
100
46.6
70.2
N.A.
N.A.
49.4
48.2
N.A.
51.4
75.6
50.9
50.9
N.A.
N.A.
N.A.
43.9
44.9
P-Site Identity:
100
0
100
N.A.
N.A.
40
40
N.A.
40
53.3
46.6
40
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
20
100
N.A.
N.A.
46.6
46.6
N.A.
46.6
73.3
53.3
46.6
N.A.
N.A.
N.A.
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
28
0
10
0
0
0
46
0
46
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
28
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
73
0
0
10
0
0
% D
% Glu:
37
19
0
0
28
10
0
10
0
0
0
0
0
0
19
% E
% Phe:
10
10
10
0
0
0
19
0
10
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
64
0
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
19
0
0
10
0
% I
% Lys:
0
0
0
19
10
19
0
0
0
19
0
0
10
0
0
% K
% Leu:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% L
% Met:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
37
0
37
0
0
73
10
10
0
0
10
0
% P
% Gln:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
0
0
10
10
10
10
% R
% Ser:
19
0
10
0
10
19
19
0
0
0
0
0
19
0
10
% S
% Thr:
10
0
0
10
0
0
0
0
0
0
0
46
0
0
0
% T
% Val:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
73
0
0
0
19
73
0
0
73
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _