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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPLA
All Species:
11.52
Human Site:
S189
Identified Species:
23.03
UniProt:
B0YJ81
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B0YJ81
NP_055056.3
288
32388
S189
R
Y
S
F
Y
T
F
S
L
L
D
H
L
P
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091308
288
32464
S189
R
Y
S
F
Y
T
F
S
L
L
D
H
L
P
Y
Dog
Lupus familis
XP_850968
216
25210
Y131
Y
L
I
K
W
A
R
Y
T
L
F
I
V
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY80
281
32308
D185
F
Y
T
F
S
L
L
D
H
L
P
H
F
I
K
Rat
Rattus norvegicus
NP_001094471
248
28631
Y163
H
F
I
K
W
A
R
Y
N
F
F
I
I
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519816
207
23678
R122
P
Y
L
I
K
W
T
R
Y
T
L
F
I
A
L
Chicken
Gallus gallus
Q5ZM57
362
42817
S265
R
Y
P
Y
Y
M
L
S
C
M
G
I
E
W
K
Frog
Xenopus laevis
NP_001088094
240
27946
Y155
Y
F
I
K
W
A
R
Y
N
L
F
I
V
L
Y
Zebra Danio
Brachydanio rerio
Q7SY06
359
42393
A262
R
Y
P
F
Y
M
L
A
C
I
D
T
E
W
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796799
235
26468
Y150
Y
V
L
M
W
L
R
Y
T
L
F
I
V
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZB2
221
25308
L136
G
F
A
P
S
W
H
L
W
L
R
Y
S
S
F
Baker's Yeast
Sacchar. cerevisiae
P40857
217
24492
G132
F
M
L
V
F
K
N
G
A
P
K
I
L
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
47.9
N.A.
82.2
80.5
N.A.
41.3
22.9
65.6
22.8
N.A.
N.A.
N.A.
N.A.
44.1
Protein Similarity:
100
N.A.
98.2
62.8
N.A.
88.8
85
N.A.
50.6
43.6
77
42
N.A.
N.A.
N.A.
N.A.
61.4
P-Site Identity:
100
N.A.
100
13.3
N.A.
26.6
6.6
N.A.
6.6
26.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
26.6
N.A.
33.3
26.6
N.A.
13.3
40
33.3
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.2
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
25
0
9
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
25
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% E
% Phe:
17
25
0
34
9
0
17
0
0
9
34
9
9
0
9
% F
% Gly:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% G
% His:
9
0
0
0
0
0
9
0
9
0
0
25
0
0
0
% H
% Ile:
0
0
25
9
0
0
0
0
0
9
0
50
17
17
0
% I
% Lys:
0
0
0
25
9
9
0
0
0
0
9
0
0
0
25
% K
% Leu:
0
9
25
0
0
17
25
9
17
59
9
0
25
34
17
% L
% Met:
0
9
0
9
0
17
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% N
% Pro:
9
0
17
9
0
0
0
0
0
9
9
0
0
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
34
0
0
0
0
0
34
9
0
0
9
0
0
0
0
% R
% Ser:
0
0
17
0
17
0
0
25
0
0
0
0
9
9
0
% S
% Thr:
0
0
9
0
0
17
9
0
17
9
0
9
0
0
0
% T
% Val:
0
9
0
9
0
0
0
0
0
0
0
0
25
0
0
% V
% Trp:
0
0
0
0
34
17
0
0
9
0
0
0
0
17
0
% W
% Tyr:
25
50
0
9
34
0
0
34
9
0
0
9
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _