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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESPN All Species: 7.88
Human Site: S232 Identified Species: 28.89
UniProt: B1AK53 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens B1AK53 NP_113663.2 854 91733 S232 L V S C T D V S L S E Q D K D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086470 1005 108024 G231 L V T F T D I G L T A R D N E
Dog Lupus familis XP_546751 854 91679 S232 L V S C T D V S L S E Q D K D
Cat Felis silvestris
Mouse Mus musculus Q9ET47 871 94479 S232 L V S F A D V S F S E Q D H D
Rat Rattus norvegicus Q63618 837 90550 V231 W L V S F A D V S F E Q D H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523384 1436 155315 R403 D I I Y N R V R D L F V D S D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791856 870 93835 N227 Y L I S H G A N V N K G D N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 30.5 90.6 N.A. 76.3 78.6 N.A. N.A. N.A. N.A. N.A. N.A. 20.6 N.A. N.A. 20.2
Protein Similarity: 100 N.A. 43.8 93 N.A. 83 85.3 N.A. N.A. N.A. N.A. N.A. N.A. 32.2 N.A. N.A. 37.1
P-Site Identity: 100 N.A. 40 100 N.A. 73.3 26.6 N.A. N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 73.3 100 N.A. 73.3 33.3 N.A. N.A. N.A. N.A. N.A. N.A. 26.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 15 15 0 0 0 15 0 0 0 0 % A
% Cys: 0 0 0 29 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 58 15 0 15 0 0 0 100 0 86 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 58 0 0 0 15 % E
% Phe: 0 0 0 29 15 0 0 0 15 15 15 0 0 0 0 % F
% Gly: 0 0 0 0 0 15 0 15 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 15 0 0 0 0 0 0 0 0 29 0 % H
% Ile: 0 15 29 0 0 0 15 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 15 0 0 29 0 % K
% Leu: 58 29 0 0 0 0 0 0 43 15 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 0 0 15 0 15 0 0 0 29 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 % Q
% Arg: 0 0 0 0 0 15 0 15 0 0 0 15 0 0 0 % R
% Ser: 0 0 43 29 0 0 0 43 15 43 0 0 0 15 0 % S
% Thr: 0 0 15 0 43 0 0 0 0 15 0 0 0 0 0 % T
% Val: 0 58 15 0 0 0 58 15 15 0 0 15 0 0 0 % V
% Trp: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _