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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESPN All Species: 6.36
Human Site: S312 Identified Species: 23.33
UniProt: B1AK53 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens B1AK53 NP_113663.2 854 91733 S312 G Y T A A D L S D F N G H S H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086470 1005 108024 A311 G Y T A A D L A E Y H G H R D
Dog Lupus familis XP_546751 854 91679 S312 G Y T A A D L S D Y N G H S H
Cat Felis silvestris
Mouse Mus musculus Q9ET47 871 94479 A312 G Y T A A D L A E F N G H T H
Rat Rattus norvegicus Q63618 837 90550 A311 G Y T A A D L A D F N G H T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523384 1436 155315 S622 S S S N I A Q S S S S N N N N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791856 870 93835 N328 I S H G A N V N K G E N N G M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 30.5 90.6 N.A. 76.3 78.6 N.A. N.A. N.A. N.A. N.A. N.A. 20.6 N.A. N.A. 20.2
Protein Similarity: 100 N.A. 43.8 93 N.A. 83 85.3 N.A. N.A. N.A. N.A. N.A. N.A. 32.2 N.A. N.A. 37.1
P-Site Identity: 100 N.A. 60 93.3 N.A. 80 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 86.6 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. 40 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 72 86 15 0 43 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 72 0 0 43 0 0 0 0 0 15 % D
% Glu: 0 0 0 0 0 0 0 0 29 0 15 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 % F
% Gly: 72 0 0 15 0 0 0 0 0 15 0 72 0 15 0 % G
% His: 0 0 15 0 0 0 0 0 0 0 15 0 72 0 58 % H
% Ile: 15 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 72 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 15 0 15 0 15 0 0 58 29 29 15 15 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 15 29 15 0 0 0 0 43 15 15 15 0 0 29 0 % S
% Thr: 0 0 72 0 0 0 0 0 0 0 0 0 0 29 0 % T
% Val: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 72 0 0 0 0 0 0 0 29 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _