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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESPN All Species: 11.21
Human Site: T706 Identified Species: 41.11
UniProt: B1AK53 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens B1AK53 NP_113663.2 854 91733 T706 L S P V R S P T P P A A G F Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086470 1005 108024 G783 Q E A T R S P G P P S L P G E
Dog Lupus familis XP_546751 854 91679 T706 P S R A R S P T P P A A G P Q
Cat Felis silvestris
Mouse Mus musculus Q9ET47 871 94479 T724 P S R T R S P T P P A S G S Q
Rat Rattus norvegicus Q63618 837 90550 T690 P S R A R S P T P P A S G P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523384 1436 155315 T1183 M Q C L T S S T E T Y L K S D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791856 870 93835 G705 L H H A V Q N G N L D V V K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 30.5 90.6 N.A. 76.3 78.6 N.A. N.A. N.A. N.A. N.A. N.A. 20.6 N.A. N.A. 20.2
Protein Similarity: 100 N.A. 43.8 93 N.A. 83 85.3 N.A. N.A. N.A. N.A. N.A. N.A. 32.2 N.A. N.A. 37.1
P-Site Identity: 100 N.A. 33.3 73.3 N.A. 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 46.6 73.3 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. N.A. N.A. 26.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 43 0 0 0 0 0 0 58 29 0 0 0 % A
% Cys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 15 % D
% Glu: 0 15 0 0 0 0 0 0 15 0 0 0 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % F
% Gly: 0 0 0 0 0 0 0 29 0 0 0 0 58 15 0 % G
% His: 0 15 15 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 15 15 0 % K
% Leu: 29 0 0 15 0 0 0 0 0 15 0 29 0 0 0 % L
% Met: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 15 0 0 0 0 0 0 % N
% Pro: 43 0 15 0 0 0 72 0 72 72 0 0 15 29 0 % P
% Gln: 15 15 0 0 0 15 0 0 0 0 0 0 0 0 58 % Q
% Arg: 0 0 43 0 72 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 58 0 0 0 86 15 0 0 0 15 29 0 29 0 % S
% Thr: 0 0 0 29 15 0 0 72 0 15 0 0 0 0 0 % T
% Val: 0 0 0 15 15 0 0 0 0 0 0 15 15 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _