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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM1
All Species:
33.94
Human Site:
S216
Identified Species:
67.88
UniProt:
B1AKI9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B1AKI9
NP_543016.1
464
52107
S216
K
D
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Chimpanzee
Pan troglodytes
XP_525268
582
65976
S334
K
D
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Rhesus Macaque
Macaca mulatta
XP_001083877
579
64782
S331
K
E
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Dog
Lupus familis
XP_542888
464
52096
S216
K
E
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
S206
K
E
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Rat
Rattus norvegicus
XP_001081313
642
71420
S394
K
E
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
E189
E
Y
D
Y
I
D
G
E
G
D
W
S
P
W
S
Chicken
Gallus gallus
XP_415036
525
59285
Y277
K
E
Q
P
E
Y
D
Y
I
D
G
E
G
D
W
Frog
Xenopus laevis
Q8QFV1
449
50956
Y201
K
E
Q
P
E
Y
D
Y
V
D
G
E
G
D
W
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
Y213
R
T
Q
T
E
Y
D
Y
I
D
G
E
G
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
N208
T
D
E
I
E
Y
E
N
V
D
Q
S
W
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
G153
R
Q
P
G
L
A
S
G
A
P
G
H
H
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
74.9
95.6
N.A.
91.8
63.8
N.A.
77.5
72.5
77.3
69.6
N.A.
N.A.
22.6
N.A.
31.4
Protein Similarity:
100
78
76.8
97.1
N.A.
93.7
67.2
N.A.
84.2
79.4
86.4
78.6
N.A.
N.A.
41.3
N.A.
46.7
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
80
80
66.6
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
86.6
73.3
N.A.
N.A.
46.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
9
0
0
9
75
0
0
92
0
0
0
75
0
% D
% Glu:
9
50
9
0
84
0
9
9
0
0
0
75
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
9
9
9
0
84
0
75
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
17
0
0
0
0
0
0
% I
% Lys:
67
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
67
0
0
0
0
0
9
0
0
9
0
9
% P
% Gln:
0
9
75
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
9
50
0
0
0
17
0
0
9
% S
% Thr:
9
9
0
9
0
0
0
0
50
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
9
75
% W
% Tyr:
0
9
0
9
0
84
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _