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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM1
All Species:
22.73
Human Site:
S448
Identified Species:
45.45
UniProt:
B1AKI9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B1AKI9
NP_543016.1
464
52107
S448
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Chimpanzee
Pan troglodytes
XP_525268
582
65976
S566
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Rhesus Macaque
Macaca mulatta
XP_001083877
579
64782
S563
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Dog
Lupus familis
XP_542888
464
52096
S448
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
S438
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Rat
Rattus norvegicus
XP_001081313
642
71420
S626
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
P418
G
Q
K
C
T
E
N
P
S
D
E
D
Y
F
K
Chicken
Gallus gallus
XP_415036
525
59285
N509
N
G
Q
K
C
T
E
N
P
T
D
E
D
Y
Y
Frog
Xenopus laevis
Q8QFV1
449
50956
N433
N
G
Q
K
C
T
E
N
P
S
E
D
D
Y
L
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
N445
N
G
Q
K
C
A
E
N
P
Q
D
E
D
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
N439
N
E
N
A
C
Q
A
N
P
D
D
E
E
Y
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
I382
N
D
R
E
C
A
D
I
P
D
L
Q
T
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
74.9
95.6
N.A.
91.8
63.8
N.A.
77.5
72.5
77.3
69.6
N.A.
N.A.
22.6
N.A.
31.4
Protein Similarity:
100
78
76.8
97.1
N.A.
93.7
67.2
N.A.
84.2
79.4
86.4
78.6
N.A.
N.A.
41.3
N.A.
46.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
80
73.3
73.3
N.A.
N.A.
40
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
93.3
100
80
N.A.
N.A.
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
17
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
92
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
25
75
17
75
0
0
% D
% Glu:
0
9
0
9
0
9
75
0
0
0
17
75
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% F
% Gly:
9
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
50
% I
% Lys:
0
0
9
75
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
92
0
9
0
0
0
9
34
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
92
0
0
0
0
0
0
% P
% Gln:
0
9
75
0
0
9
0
0
0
9
0
9
0
0
9
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
9
59
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
67
0
0
0
9
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
84
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _