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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM1
All Species:
27.58
Human Site:
T205
Identified Species:
55.15
UniProt:
B1AKI9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B1AKI9
NP_543016.1
464
52107
T205
H
T
A
P
G
H
R
T
F
E
T
K
D
Q
P
Chimpanzee
Pan troglodytes
XP_525268
582
65976
T323
H
T
A
P
G
H
R
T
F
E
T
K
D
Q
P
Rhesus Macaque
Macaca mulatta
XP_001083877
579
64782
T320
H
T
A
P
G
H
R
T
F
E
T
K
E
Q
P
Dog
Lupus familis
XP_542888
464
52096
T205
R
P
A
P
G
H
R
T
F
E
A
K
E
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
T195
R
P
A
P
G
H
R
T
F
E
T
K
E
Q
P
Rat
Rattus norvegicus
XP_001081313
642
71420
T383
R
P
A
P
G
H
R
T
F
E
T
K
E
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
K178
S
H
R
T
F
E
T
K
E
Q
T
E
Y
D
Y
Chicken
Gallus gallus
XP_415036
525
59285
T266
G
H
A
P
S
H
R
T
F
E
S
K
E
Q
P
Frog
Xenopus laevis
Q8QFV1
449
50956
T190
R
Q
V
P
S
H
R
T
F
D
T
K
E
Q
P
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
G202
R
R
V
K
S
E
A
G
A
G
S
R
T
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
E197
E
L
I
G
S
Y
D
E
L
P
T
T
D
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
R142
S
P
P
P
S
D
H
R
V
S
L
R
Q
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
74.9
95.6
N.A.
91.8
63.8
N.A.
77.5
72.5
77.3
69.6
N.A.
N.A.
22.6
N.A.
31.4
Protein Similarity:
100
78
76.8
97.1
N.A.
93.7
67.2
N.A.
84.2
79.4
86.4
78.6
N.A.
N.A.
41.3
N.A.
46.7
P-Site Identity:
100
100
93.3
73.3
N.A.
80
80
N.A.
6.6
66.6
60
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
20
80
73.3
20
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
59
0
0
0
9
0
9
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
0
9
0
0
25
9
0
% D
% Glu:
9
0
0
0
0
17
0
9
9
59
0
9
50
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
67
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
50
0
0
9
0
9
0
0
0
0
9
% G
% His:
25
17
0
0
0
67
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
0
0
9
0
0
0
67
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
34
9
75
0
0
0
0
0
9
0
0
0
9
67
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
0
0
9
75
0
% Q
% Arg:
42
9
9
0
0
0
67
9
0
0
0
17
0
0
0
% R
% Ser:
17
0
0
0
42
0
0
0
0
9
17
0
0
0
0
% S
% Thr:
0
25
0
9
0
0
9
67
0
0
67
9
9
0
9
% T
% Val:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _