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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISM1
All Species:
36.67
Human Site:
Y180
Identified Species:
73.33
UniProt:
B1AKI9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B1AKI9
NP_543016.1
464
52107
Y180
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
Chimpanzee
Pan troglodytes
XP_525268
582
65976
Y298
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
Rhesus Macaque
Macaca mulatta
XP_001083877
579
64782
Y295
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
Dog
Lupus familis
XP_542888
464
52096
Y180
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
Cat
Felis silvestris
Mouse
Mus musculus
A2ATD1
454
51126
Y170
S
G
D
Q
D
D
K
Y
D
S
T
S
D
D
S
Rat
Rattus norvegicus
XP_001081313
642
71420
Y358
S
G
D
Q
D
D
K
Y
D
S
T
S
D
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515088
433
49392
T153
D
Y
K
Y
D
S
T
T
E
D
S
N
F
L
N
Chicken
Gallus gallus
XP_415036
525
59285
Y241
S
G
D
Q
D
Y
K
Y
D
S
T
T
E
D
S
Frog
Xenopus laevis
Q8QFV1
449
50956
Y165
Y
G
D
Q
D
Y
K
Y
D
S
T
T
E
D
S
Zebra Danio
Brachydanio rerio
Q5EGE1
461
51157
Y177
P
E
E
Q
D
Y
P
Y
E
S
N
T
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120589
455
53322
S172
R
I
K
S
K
K
E
S
F
V
V
I
E
R
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198390
398
44790
E117
D
E
E
E
D
A
A
E
I
D
N
R
L
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
74.9
95.6
N.A.
91.8
63.8
N.A.
77.5
72.5
77.3
69.6
N.A.
N.A.
22.6
N.A.
31.4
Protein Similarity:
100
78
76.8
97.1
N.A.
93.7
67.2
N.A.
84.2
79.4
86.4
78.6
N.A.
N.A.
41.3
N.A.
46.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
86.6
80
46.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
33.3
100
93.3
73.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
67
0
92
17
0
0
67
17
0
0
50
75
0
% D
% Glu:
0
17
17
9
0
0
9
9
17
0
0
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
17
0
9
9
67
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
17
% N
% Pro:
9
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
59
0
0
9
0
9
0
9
0
75
9
50
0
0
75
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
67
25
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
9
0
59
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _