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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO9A All Species: 19.39
Human Site: S2259 Identified Species: 38.79
UniProt: B2RTY4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens B2RTY4 NP_008832.2 2548 292778 S2259 K A R L K D I S S L E F A E N
Chimpanzee Pan troglodytes XP_001175044 2547 292555 S2259 K A R L K D I S S L E F A E N
Rhesus Macaque Macaca mulatta XP_001089813 2404 275033 S2115 K A R L K D I S S L E F A E N
Dog Lupus familis XP_544755 2557 293928 S2268 K A R L K D I S S L E F A E N
Cat Felis silvestris
Mouse Mus musculus Q8C170 2542 292101 S2261 K A R L K D I S S L E F A E N
Rat Rattus norvegicus Q9Z1N3 2626 301363 K2337 E F A E N K A K T R L S L I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506807 1618 185462 L1337 V L N I F Q S L L D E F S R G
Chicken Gallus gallus Q02440 1829 212364 E1548 C L K Q Y S G E E G F M K H N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001924043 2530 291054 N2248 L I I C E Q M N K Y R A R L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3Z6 2167 250290 S1885 K D F C N N I S Q R L S L R T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91443 2098 239766 D1817 R L G L K S S D G F S L F V K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 E1293 E Y V S L V T E L K D D F E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 81.3 91.8 N.A. 88.6 86 N.A. 32.4 23.9 N.A. 64.5 N.A. 21.3 N.A. 21.7 N.A.
Protein Similarity: 100 99.6 84.7 95 N.A. 92.9 90.5 N.A. 45 41 N.A. 76.3 N.A. 39.1 N.A. 40.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 13.3 6.6 N.A. 0 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 26.6 13.3 N.A. 20 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 42 9 0 0 0 9 0 0 0 0 9 42 0 9 % A
% Cys: 9 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 42 0 9 0 9 9 9 0 0 0 % D
% Glu: 17 0 0 9 9 0 0 17 9 0 50 0 0 50 0 % E
% Phe: 0 9 9 0 9 0 0 0 0 9 9 50 17 0 0 % F
% Gly: 0 0 9 0 0 0 9 0 9 9 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 9 9 9 0 0 50 0 0 0 0 0 0 9 0 % I
% Lys: 50 0 9 0 50 9 0 9 9 9 0 0 9 0 17 % K
% Leu: 9 25 0 50 9 0 0 9 17 42 17 9 17 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 17 9 0 9 0 0 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 17 0 0 9 0 0 0 0 0 0 % Q
% Arg: 9 0 42 0 0 0 0 0 0 17 9 0 9 17 9 % R
% Ser: 0 0 0 9 0 17 17 50 42 0 9 17 9 0 0 % S
% Thr: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 9 % T
% Val: 9 0 9 0 0 9 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _