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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO9A
All Species:
23.94
Human Site:
Y486
Identified Species:
47.88
UniProt:
B2RTY4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B2RTY4
NP_008832.2
2548
292778
Y486
G
E
K
L
I
L
P
Y
K
L
A
E
A
V
T
Chimpanzee
Pan troglodytes
XP_001175044
2547
292555
Y486
G
E
K
L
I
L
P
Y
K
L
A
E
A
V
T
Rhesus Macaque
Macaca mulatta
XP_001089813
2404
275033
E443
E
Q
E
E
Y
R
T
E
G
I
S
W
H
N
I
Dog
Lupus familis
XP_544755
2557
293928
Y486
G
E
K
L
I
L
P
Y
K
L
A
E
A
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C170
2542
292101
Y486
G
E
K
L
I
L
P
Y
K
L
A
E
A
V
T
Rat
Rattus norvegicus
Q9Z1N3
2626
301363
Y486
G
E
K
L
I
L
P
Y
K
L
A
E
A
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506807
1618
185462
Chicken
Gallus gallus
Q02440
1829
212364
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001924043
2530
291054
Y486
G
E
K
L
I
V
P
Y
K
L
A
E
A
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Z6
2167
250290
E231
V
I
E
G
A
K
I
E
Q
Y
L
L
E
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91443
2098
239766
T162
G
E
S
G
A
G
K
T
E
S
T
K
L
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19524
1574
180662
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
81.3
91.8
N.A.
88.6
86
N.A.
32.4
23.9
N.A.
64.5
N.A.
21.3
N.A.
21.7
N.A.
Protein Similarity:
100
99.6
84.7
95
N.A.
92.9
90.5
N.A.
45
41
N.A.
76.3
N.A.
39.1
N.A.
40.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
0
N.A.
86.6
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
0
0
N.A.
93.3
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
0
50
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
59
17
9
0
0
0
17
9
0
0
50
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
59
0
0
17
0
9
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
0
50
0
9
0
0
9
0
0
0
0
9
% I
% Lys:
0
0
50
0
0
9
9
0
50
0
0
9
0
9
0
% K
% Leu:
0
0
0
50
0
42
0
0
0
50
9
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
0
0
0
9
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
9
0
0
0
50
% T
% Val:
9
0
0
0
0
9
0
0
0
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
50
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _