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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VWC2L
All Species:
17.27
Human Site:
Y48
Identified Species:
63.33
UniProt:
B2RUY7
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
B2RUY7
NP_001073969.1
222
24570
Y48
D
N
L
I
F
D
D
Y
R
G
K
G
C
V
D
Chimpanzee
Pan troglodytes
XP_001153682
325
35249
Y150
E
E
Y
V
Y
P
D
Y
R
G
K
G
C
V
D
Rhesus Macaque
Macaca mulatta
XP_001085881
245
26719
K47
P
E
Q
P
G
Q
E
K
R
E
H
A
S
R
D
Dog
Lupus familis
XP_545633
323
35300
Y48
D
N
L
I
F
D
D
Y
R
G
K
G
C
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q505H4
222
24509
Y48
D
N
L
I
F
D
D
Y
R
G
K
G
C
V
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518383
130
14596
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0UZC8
223
24490
Y48
N
D
I
I
F
D
D
Y
R
G
K
G
C
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
37.5
67.4
N.A.
98.6
N.A.
N.A.
54
N.A.
N.A.
78.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51
51.8
67.8
N.A.
99.5
N.A.
N.A.
55.8
N.A.
N.A.
87.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
13.3
100
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
20
100
N.A.
100
N.A.
N.A.
0
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% C
% Asp:
43
15
0
0
0
58
72
0
0
0
0
0
0
0
86
% D
% Glu:
15
29
0
0
0
0
15
0
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
58
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
0
0
0
0
72
0
72
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
0
0
15
58
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
15
0
0
72
0
0
0
0
% K
% Leu:
0
0
43
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
43
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
15
0
15
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
15
0
0
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
86
0
0
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
0
0
72
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
15
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _