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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNASE2
All Species:
13.64
Human Site:
Y20
Identified Species:
27.27
UniProt:
O00115
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00115
NP_001366.1
360
39581
Y20
P
A
G
A
L
T
C
Y
G
D
S
G
Q
P
V
Chimpanzee
Pan troglodytes
XP_001170388
360
39643
Y20
P
A
G
A
L
T
C
Y
G
D
S
G
Q
P
V
Rhesus Macaque
Macaca mulatta
XP_001106353
361
41660
C32
L
G
T
A
T
I
S
C
R
N
E
E
G
K
A
Dog
Lupus familis
XP_533902
364
39810
Y23
P
V
R
T
L
T
C
Y
G
D
S
G
Q
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P56542
353
38792
C22
V
P
A
E
A
L
S
C
Y
G
D
S
G
Q
P
Rat
Rattus norvegicus
Q9QZK8
350
38157
Y23
P
A
E
A
L
S
C
Y
G
D
S
G
R
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507235
348
37739
S19
P
G
A
A
T
V
I
S
C
Y
G
D
T
G
K
Chicken
Gallus gallus
NP_001032927
363
40865
C29
L
W
A
A
E
I
S
C
R
N
E
D
G
E
A
Frog
Xenopus laevis
NP_001086671
349
38720
S21
V
S
S
F
A
A
I
S
C
Y
G
D
Q
G
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650672
366
41322
K26
A
K
S
K
V
S
C
K
D
E
A
G
N
D
V
Honey Bee
Apis mellifera
XP_396933
375
42824
D29
Y
N
K
L
Q
C
K
D
E
N
N
L
S
V
D
Nematode Worm
Caenorhab. elegans
P34387
367
41212
I12
F
V
L
I
F
S
V
I
F
T
T
G
N
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
36
71.9
N.A.
69.7
70.8
N.A.
62.5
38.2
46.9
N.A.
N.A.
32.7
35.7
33.5
N.A.
Protein Similarity:
100
99.4
52.9
81.5
N.A.
81.6
81.3
N.A.
75
55.3
65
N.A.
N.A.
49.1
51.2
50.6
N.A.
P-Site Identity:
100
100
6.6
80
N.A.
0
80
N.A.
13.3
6.6
6.6
N.A.
N.A.
20
0
6.6
N.A.
P-Site Similarity:
100
100
13.3
80
N.A.
0
93.3
N.A.
13.3
13.3
13.3
N.A.
N.A.
46.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
25
50
17
9
0
0
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
9
42
25
17
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
9
34
9
25
0
9
9
% D
% Glu:
0
0
9
9
9
0
0
0
9
9
17
9
0
9
0
% E
% Phe:
9
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
17
17
0
0
0
0
0
34
9
17
50
25
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
17
17
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
9
0
0
9
9
0
0
0
0
0
9
17
% K
% Leu:
17
0
9
9
34
9
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
25
9
0
17
0
0
% N
% Pro:
42
9
0
0
0
0
0
0
0
0
0
0
0
34
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
34
9
9
% Q
% Arg:
0
0
9
0
0
0
0
0
17
0
0
0
9
0
0
% R
% Ser:
0
9
17
0
0
25
25
17
0
0
34
9
9
0
0
% S
% Thr:
0
0
9
9
17
25
0
0
0
9
9
0
9
0
0
% T
% Val:
17
17
0
0
9
9
9
0
0
0
0
0
0
9
42
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
34
9
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _