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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPS
All Species:
10.3
Human Site:
S149
Identified Species:
17.44
UniProt:
O00116
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00116
NP_003650.1
658
72912
S149
H
K
T
T
S
K
A
S
L
N
P
S
D
T
P
Chimpanzee
Pan troglodytes
XP_001154263
658
72867
S149
H
K
T
T
S
K
A
S
L
N
P
S
D
T
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545543
659
72756
S150
H
K
T
T
S
K
A
S
L
N
P
N
D
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I1
645
71665
E149
A
P
P
S
I
V
N
E
D
F
L
Q
E
L
K
Rat
Rattus norvegicus
Q9EQR2
644
71569
E148
A
P
P
S
I
V
N
E
D
F
L
Q
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515333
574
64377
R120
L
R
E
G
M
F
E
R
I
P
D
I
V
L
W
Chicken
Gallus gallus
XP_421987
636
70768
N139
D
V
P
P
S
I
V
N
E
E
F
L
Q
D
L
Frog
Xenopus laevis
NP_001086573
627
69809
I140
F
L
Q
D
I
K
A
I
G
I
S
Y
S
Q
D
Zebra Danio
Brachydanio rerio
A1L258
533
58696
S79
R
V
T
Q
E
D
L
S
F
F
R
A
L
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
G141
D
R
L
V
R
C
H
G
Q
T
L
N
D
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
W140
R
L
P
D
I
V
V
W
P
K
S
E
H
E
I
Sea Urchin
Strong. purpuratus
XP_001187122
414
46159
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AX4
567
62157
Q113
V
P
K
E
L
I
S
Q
L
K
T
I
L
E
D
Baker's Yeast
Sacchar. cerevisiae
P32891
587
65274
L132
Y
S
D
A
K
S
D
L
D
A
H
S
D
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
93.4
N.A.
90.7
89.8
N.A.
80.8
78.5
77.3
21.2
N.A.
50.9
N.A.
47.7
41.6
Protein Similarity:
100
99.8
N.A.
96.2
N.A.
94.6
94.5
N.A.
84.1
87
86.3
36.6
N.A.
66.4
N.A.
63
53.9
P-Site Identity:
100
100
N.A.
93.3
N.A.
0
0
N.A.
0
6.6
13.3
20
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
13.3
N.A.
13.3
13.3
13.3
26.6
N.A.
20
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
0
29
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
15
0
8
8
0
22
0
8
0
36
8
15
% D
% Glu:
0
0
8
8
8
0
8
15
8
8
0
8
15
15
0
% E
% Phe:
8
0
0
0
0
8
0
0
8
22
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% G
% His:
22
0
0
0
0
0
8
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
29
15
0
8
8
8
0
15
0
8
8
% I
% Lys:
0
22
8
0
8
29
0
0
0
15
0
0
0
0
15
% K
% Leu:
8
15
8
0
8
0
8
8
29
0
22
8
15
29
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
8
0
22
0
15
0
0
0
% N
% Pro:
0
22
29
8
0
0
0
0
8
8
22
0
0
0
29
% P
% Gln:
0
0
8
8
0
0
0
8
8
0
0
15
8
8
0
% Q
% Arg:
15
15
0
0
8
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
15
29
8
8
29
0
0
15
22
8
0
0
% S
% Thr:
0
0
29
22
0
0
0
0
0
8
8
0
0
29
0
% T
% Val:
8
15
0
8
0
22
15
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _