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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPS
All Species:
11.82
Human Site:
S176
Identified Species:
20
UniProt:
O00116
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00116
NP_003650.1
658
72912
S176
K
E
T
N
I
S
Y
S
Q
E
A
D
D
R
V
Chimpanzee
Pan troglodytes
XP_001154263
658
72867
S176
K
E
T
N
I
S
Y
S
Q
E
A
D
D
R
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545543
659
72756
S177
K
E
I
N
I
S
Y
S
Q
E
A
D
D
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I1
645
71665
H176
R
V
F
R
A
H
G
H
C
L
H
E
I
F
L
Rat
Rattus norvegicus
Q9EQR2
644
71569
H175
R
V
F
R
A
H
G
H
C
L
H
E
I
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515333
574
64377
C147
L
A
C
K
H
N
L
C
I
I
P
F
G
G
G
Chicken
Gallus gallus
XP_421987
636
70768
G166
D
R
V
F
R
A
H
G
H
C
L
H
E
I
F
Frog
Xenopus laevis
NP_001086573
627
69809
R167
L
H
E
I
F
T
L
R
E
G
M
F
K
R
I
Zebra Danio
Brachydanio rerio
A1L258
533
58696
T106
S
N
V
D
W
L
K
T
V
Q
G
S
S
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
H168
L
V
V
W
P
R
C
H
D
E
V
V
Q
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
G167
A
I
I
P
I
G
G
G
T
S
V
T
N
A
L
Sea Urchin
Strong. purpuratus
XP_001187122
414
46159
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AX4
567
62157
H140
G
K
P
Q
N
S
F
H
K
A
V
N
I
P
D
Baker's Yeast
Sacchar. cerevisiae
P32891
587
65274
T159
R
I
I
L
F
P
H
T
T
E
E
V
S
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
93.4
N.A.
90.7
89.8
N.A.
80.8
78.5
77.3
21.2
N.A.
50.9
N.A.
47.7
41.6
Protein Similarity:
100
99.8
N.A.
96.2
N.A.
94.6
94.5
N.A.
84.1
87
86.3
36.6
N.A.
66.4
N.A.
63
53.9
P-Site Identity:
100
100
N.A.
93.3
N.A.
0
0
N.A.
0
0
6.6
6.6
N.A.
13.3
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
20
20
N.A.
6.6
20
26.6
26.6
N.A.
13.3
N.A.
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
8
0
0
0
8
22
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
8
8
15
8
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
8
0
0
22
22
8
8
% D
% Glu:
0
22
8
0
0
0
0
0
8
36
8
15
8
0
0
% E
% Phe:
0
0
15
8
15
0
8
0
0
0
0
15
0
15
8
% F
% Gly:
8
0
0
0
0
8
22
15
0
8
8
0
8
8
8
% G
% His:
0
8
0
0
8
15
15
29
8
0
15
8
0
0
0
% H
% Ile:
0
15
22
8
29
0
0
0
8
8
0
0
22
8
15
% I
% Lys:
22
8
0
8
0
0
8
0
8
0
0
0
8
8
0
% K
% Leu:
22
0
0
8
0
8
15
0
0
15
8
0
0
8
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
22
8
8
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
8
8
8
8
0
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
22
8
0
0
8
0
0
% Q
% Arg:
22
8
0
15
8
8
0
8
0
0
0
0
0
29
0
% R
% Ser:
8
0
0
0
0
29
0
22
0
8
0
8
15
0
0
% S
% Thr:
0
0
15
0
0
8
0
15
15
0
0
8
0
0
0
% T
% Val:
0
22
22
0
0
0
0
0
8
0
22
15
0
0
36
% V
% Trp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _