KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPS
All Species:
31.52
Human Site:
S612
Identified Species:
53.33
UniProt:
O00116
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00116
NP_003650.1
658
72912
S612
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Chimpanzee
Pan troglodytes
XP_001154263
658
72867
S612
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545543
659
72756
S613
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I1
645
71665
S599
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Rat
Rattus norvegicus
Q9EQR2
644
71569
S598
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515333
574
64377
V535
S
L
S
H
H
H
G
V
G
K
L
R
K
Q
W
Chicken
Gallus gallus
XP_421987
636
70768
S590
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Frog
Xenopus laevis
NP_001086573
627
69809
S581
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Zebra Danio
Brachydanio rerio
A1L258
533
58696
R494
H
G
L
G
L
K
K
R
N
Y
I
Y
Y
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
S563
E
I
L
S
C
G
G
S
L
S
H
H
H
G
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
L557
K
I
R
K
Q
W
M
L
T
T
N
G
A
V
G
Sea Urchin
Strong. purpuratus
XP_001187122
414
46159
I375
S
L
S
H
H
H
G
I
G
K
H
R
K
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AX4
567
62157
K528
G
V
G
T
G
K
M
K
Y
L
E
K
E
L
G
Baker's Yeast
Sacchar. cerevisiae
P32891
587
65274
L548
R
E
Y
L
L
E
E
L
G
E
A
P
V
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
93.4
N.A.
90.7
89.8
N.A.
80.8
78.5
77.3
21.2
N.A.
50.9
N.A.
47.7
41.6
Protein Similarity:
100
99.8
N.A.
96.2
N.A.
94.6
94.5
N.A.
84.1
87
86.3
36.6
N.A.
66.4
N.A.
63
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
100
100
6.6
N.A.
86.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
100
20
N.A.
93.3
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
58
8
0
0
0
8
8
0
0
8
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
8
8
8
58
72
0
22
0
0
8
0
58
15
% G
% His:
8
0
0
15
15
15
0
0
0
0
65
58
58
0
0
% H
% Ile:
0
65
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
8
0
0
8
0
15
8
8
0
15
0
8
15
0
8
% K
% Leu:
0
15
65
8
15
0
0
15
58
8
8
0
0
8
8
% L
% Met:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
8
0
0
0
0
8
0
0
0
15
0
0
0
% R
% Ser:
15
0
15
8
0
0
0
58
0
58
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
8
8
58
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
0
0
0
0
0
8
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _