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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGPS All Species: 18.18
Human Site: Y509 Identified Species: 30.77
UniProt: O00116 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00116 NP_003650.1 658 72912 Y509 Q R G Y L L T Y V I A Y I R D
Chimpanzee Pan troglodytes XP_001154263 658 72867 Y509 Q R G Y L L T Y V I A Y I R D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545543 659 72756 Y510 Q R G Y L L T Y V I A Y I R D
Cat Felis silvestris
Mouse Mus musculus Q8C0I1 645 71665 Y496 Q R G Y L L T Y V I A Y I R D
Rat Rattus norvegicus Q9EQR2 644 71569 Y495 Q R G Y L L T Y V I A Y M R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515333 574 64377 L435 A Y L R D L G L E Y Y V I G E
Chicken Gallus gallus XP_421987 636 70768 F487 Q R G Y M L T F V I A Y L R D
Frog Xenopus laevis NP_001086573 627 69809 F478 Q R G Y M L T F V I A Y L R D
Zebra Danio Brachydanio rerio A1L258 533 58696 W394 A T K I K A L W S L R E R V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V778 631 70803 F461 E R G Y I L T F V I A Y I R D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45218 597 66541 F457 H G V L G E S F E T S V P W D
Sea Urchin Strong. purpuratus XP_001187122 414 46159 M275 A Y I R D F A M D H Y I I A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94AX4 567 62157 L428 W K I R K E A L W A C Y A M A
Baker's Yeast Sacchar. cerevisiae P32891 587 65274 K448 W S V L D A D K S K D K S A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 93.4 N.A. 90.7 89.8 N.A. 80.8 78.5 77.3 21.2 N.A. 50.9 N.A. 47.7 41.6
Protein Similarity: 100 99.8 N.A. 96.2 N.A. 94.6 94.5 N.A. 84.1 87 86.3 36.6 N.A. 66.4 N.A. 63 53.9
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 13.3 80 80 0 N.A. 80 N.A. 6.6 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 100 100 13.3 N.A. 100 N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.2 21.4 N.A.
Protein Similarity: N.A. N.A. N.A. 42.1 40.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 0 0 15 15 0 0 8 58 0 8 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 22 0 8 0 8 0 8 0 0 0 65 % D
% Glu: 8 0 0 0 0 15 0 0 15 0 0 8 0 0 15 % E
% Phe: 0 0 0 0 0 8 0 29 0 0 0 0 0 0 0 % F
% Gly: 0 8 58 0 8 0 8 0 0 0 0 0 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 15 8 8 0 0 0 0 58 0 8 50 0 0 % I
% Lys: 0 8 8 0 15 0 0 8 0 8 0 8 0 0 8 % K
% Leu: 0 0 8 15 36 65 8 15 0 8 0 0 15 0 0 % L
% Met: 0 0 0 0 15 0 0 8 0 0 0 0 8 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 58 0 22 0 0 0 0 0 0 8 0 8 58 0 % R
% Ser: 0 8 0 0 0 0 8 0 15 0 8 0 8 0 0 % S
% Thr: 0 8 0 0 0 0 58 0 0 8 0 0 0 0 8 % T
% Val: 0 0 15 0 0 0 0 0 58 0 0 15 0 8 0 % V
% Trp: 15 0 0 0 0 0 0 8 8 0 0 0 0 8 0 % W
% Tyr: 0 15 0 58 0 0 0 36 0 8 15 65 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _