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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPS
All Species:
25.76
Human Site:
Y522
Identified Species:
43.59
UniProt:
O00116
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00116
NP_003650.1
658
72912
Y522
R
D
L
A
L
E
Y
Y
V
L
G
E
S
F
E
Chimpanzee
Pan troglodytes
XP_001154263
658
72867
Y522
R
D
L
A
L
E
Y
Y
V
L
G
E
S
F
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545543
659
72756
Y523
R
D
L
G
L
E
Y
Y
I
L
G
E
S
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I1
645
71665
Y509
R
D
L
G
L
E
Y
Y
V
I
G
E
S
F
E
Rat
Rattus norvegicus
Q9EQR2
644
71569
Y508
R
D
L
G
L
E
Y
Y
V
V
G
E
S
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515333
574
64377
A448
G
E
S
F
E
T
S
A
P
W
D
R
V
L
D
Chicken
Gallus gallus
XP_421987
636
70768
Y500
R
D
L
G
L
D
Y
Y
V
I
G
E
S
F
E
Frog
Xenopus laevis
NP_001086573
627
69809
Y491
R
D
L
G
M
D
Y
Y
L
I
G
E
S
F
E
Zebra Danio
Brachydanio rerio
A1L258
533
58696
E407
V
T
E
A
L
T
H
E
G
Y
T
Y
K
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
G474
R
D
F
G
L
H
Q
G
I
V
A
E
S
F
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
C470
W
D
K
V
L
S
L
C
R
N
V
K
E
L
M
Sea Urchin
Strong. purpuratus
XP_001187122
414
46159
V288
A
E
S
F
E
T
T
V
P
W
D
R
V
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AX4
567
62157
M441
M
A
P
G
H
E
A
M
I
T
D
V
C
V
P
Baker's Yeast
Sacchar. cerevisiae
P32891
587
65274
V461
A
K
I
W
T
T
D
V
A
V
P
V
S
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
93.4
N.A.
90.7
89.8
N.A.
80.8
78.5
77.3
21.2
N.A.
50.9
N.A.
47.7
41.6
Protein Similarity:
100
99.8
N.A.
96.2
N.A.
94.6
94.5
N.A.
84.1
87
86.3
36.6
N.A.
66.4
N.A.
63
53.9
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
0
80
66.6
13.3
N.A.
46.6
N.A.
13.3
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
13.3
93.3
93.3
33.3
N.A.
60
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
22
0
0
8
8
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% C
% Asp:
0
65
0
0
0
15
8
0
0
0
22
0
0
0
22
% D
% Glu:
0
15
8
0
15
43
0
8
0
0
0
58
8
0
58
% E
% Phe:
0
0
8
15
0
0
0
0
0
0
0
0
0
58
8
% F
% Gly:
8
0
0
50
0
0
0
8
8
0
50
0
0
0
0
% G
% His:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
22
22
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
8
8
0
0
% K
% Leu:
0
0
50
0
65
0
8
0
8
22
0
0
0
22
0
% L
% Met:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
15
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
58
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% R
% Ser:
0
0
15
0
0
8
8
0
0
0
0
0
65
0
0
% S
% Thr:
0
8
0
0
8
29
8
0
0
8
8
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
15
36
22
8
15
15
8
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
15
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
50
0
8
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _