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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPS
All Species:
22.73
Human Site:
Y645
Identified Species:
38.46
UniProt:
O00116
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00116
NP_003650.1
658
72912
Y645
M
L
K
S
V
K
E
Y
V
D
P
N
N
I
F
Chimpanzee
Pan troglodytes
XP_001154263
658
72867
Y645
M
L
K
S
V
K
E
Y
V
D
P
N
N
I
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545543
659
72756
Y646
M
L
K
S
V
K
E
Y
V
D
P
N
N
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0I1
645
71665
Y632
M
L
K
S
V
K
E
Y
V
D
P
S
N
I
F
Rat
Rattus norvegicus
Q9EQR2
644
71569
Y631
M
L
K
S
V
K
D
Y
V
D
P
S
N
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515333
574
64377
I567
E
Y
V
D
P
K
N
I
F
G
N
R
N
L
L
Chicken
Gallus gallus
XP_421987
636
70768
Y623
M
L
R
S
V
K
E
Y
V
D
P
N
N
I
F
Frog
Xenopus laevis
NP_001086573
627
69809
F614
M
L
R
S
V
K
N
F
V
D
P
N
N
T
F
Zebra Danio
Brachydanio rerio
A1L258
533
58696
K526
K
G
I
L
N
P
Y
K
T
L
P
D
N
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V778
631
70803
H596
L
Y
S
A
A
K
R
H
L
D
P
K
N
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45218
597
66541
I589
A
S
A
N
L
I
D
I
I
G
S
P
H
C
K
Sea Urchin
Strong. purpuratus
XP_001187122
414
46159
I407
D
R
L
D
P
D
N
I
F
G
N
Q
N
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AX4
567
62157
L560
D
I
M
N
P
G
K
L
I
P
P
H
V
C
F
Baker's Yeast
Sacchar. cerevisiae
P32891
587
65274
N580
K
I
F
K
T
D
P
N
E
P
A
N
D
Y
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
93.4
N.A.
90.7
89.8
N.A.
80.8
78.5
77.3
21.2
N.A.
50.9
N.A.
47.7
41.6
Protein Similarity:
100
99.8
N.A.
96.2
N.A.
94.6
94.5
N.A.
84.1
87
86.3
36.6
N.A.
66.4
N.A.
63
53.9
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
13.3
93.3
73.3
20
N.A.
40
N.A.
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
86.6
26.6
N.A.
66.6
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
21.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% C
% Asp:
15
0
0
15
0
15
15
0
0
58
0
8
8
0
0
% D
% Glu:
8
0
0
0
0
0
36
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
15
0
0
0
0
0
65
% F
% Gly:
0
8
0
0
0
8
0
0
0
22
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% H
% Ile:
0
15
8
0
0
8
0
22
15
0
0
0
0
58
0
% I
% Lys:
15
0
36
8
0
65
8
8
0
0
0
8
0
0
8
% K
% Leu:
8
50
8
8
8
0
0
8
8
8
0
0
0
15
8
% L
% Met:
50
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
15
8
0
22
8
0
0
15
43
79
0
8
% N
% Pro:
0
0
0
0
22
8
8
0
0
15
72
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
15
0
0
0
8
0
0
0
0
8
0
0
8
% R
% Ser:
0
8
8
50
0
0
0
0
0
0
8
15
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% T
% Val:
0
0
8
0
50
0
0
0
50
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
8
43
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _