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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK1
All Species:
36.36
Human Site:
S377
Identified Species:
61.54
UniProt:
O00141
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00141
NP_001137148.1
431
48942
S377
P
P
F
N
P
N
V
S
G
P
N
D
L
R
H
Chimpanzee
Pan troglodytes
XP_518751
605
68702
S551
P
P
F
N
P
N
V
S
G
P
N
D
L
R
H
Rhesus Macaque
Macaca mulatta
XP_001102277
637
72261
S583
P
P
F
N
P
N
V
S
G
P
N
D
L
R
H
Dog
Lupus familis
XP_849801
431
48950
S377
P
P
F
N
P
N
V
S
G
P
S
D
L
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVC6
431
48910
S377
P
P
F
N
P
N
V
S
G
P
S
D
L
R
H
Rat
Rattus norvegicus
Q06226
430
48909
G377
P
F
N
P
N
V
S
G
P
S
D
L
R
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507569
431
48976
S377
P
P
F
N
P
N
V
S
G
P
S
D
L
R
H
Chicken
Gallus gallus
Q6U1I9
432
48872
S378
P
P
F
N
P
N
V
S
G
P
S
D
L
R
H
Frog
Xenopus laevis
Q6GLY8
434
49082
S380
P
P
F
N
P
N
V
S
G
P
S
D
L
Q
H
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
T379
P
P
F
N
P
N
V
T
G
P
N
D
L
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
V544
P
P
P
F
K
P
Q
V
T
S
D
T
D
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q2PJ68
463
54273
I410
R
E
L
K
A
P
F
I
P
K
V
K
N
A
M
Sea Urchin
Strong. purpuratus
XP_001192139
440
49530
R382
I
T
P
P
Y
N
P
R
V
S
D
S
M
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12688
680
76461
N625
P
Y
K
P
A
V
S
N
S
M
D
T
S
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.7
66.2
97.6
N.A.
96.5
96.9
N.A.
95.3
95.1
88.9
86.6
N.A.
34.7
N.A.
47
62.7
Protein Similarity:
100
70.2
67.1
99
N.A.
98.6
98.6
N.A.
98.3
97.2
94.2
92.8
N.A.
47.9
N.A.
63.5
75
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
93.3
93.3
86.6
93.3
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
100
100
N.A.
20
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
29
65
8
8
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
65
8
0
0
8
0
0
0
0
0
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
8
65
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
65
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
8
65
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% M
% Asn:
0
0
8
65
8
72
0
8
0
0
29
0
8
8
0
% N
% Pro:
86
72
15
22
65
15
8
0
15
65
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
8
58
8
% R
% Ser:
0
0
0
0
0
0
15
58
8
22
36
8
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
8
0
0
15
0
8
0
% T
% Val:
0
0
0
0
0
15
65
8
8
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _