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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK1 All Species: 39.09
Human Site: S61 Identified Species: 66.15
UniProt: O00141 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00141 NP_001137148.1 431 48942 S61 V Q S I L K I S Q P Q E P E L
Chimpanzee Pan troglodytes XP_518751 605 68702 S235 V Q S I L K I S Q P Q E P E L
Rhesus Macaque Macaca mulatta XP_001102277 637 72261 S267 V Q S I L K I S Q P Q E P E L
Dog Lupus familis XP_849801 431 48950 S61 V Q S I L K I S Q P Q E P E L
Cat Felis silvestris
Mouse Mus musculus Q9WVC6 431 48910 S61 V Q S I L K M S H P Q E P E L
Rat Rattus norvegicus Q06226 430 48909 S61 V Q S Y L K I S Q P Q E P E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507569 431 48976 S61 V Q T I L K I S Q P Q E P E L
Chicken Gallus gallus Q6U1I9 432 48872 S62 V Q S I L K I S Q P Q E P E L
Frog Xenopus laevis Q6GLY8 434 49082 S64 V Q S I L N I S P P Q E S E L
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 T63 V Q S I L N L T P P Q D V E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 M229 T P S E Q T D M T D V D M A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q2PJ68 463 54273 N98 S Q H L V D N N L R S E D V R
Sea Urchin Strong. purpuratus XP_001192139 440 49530 P66 L D N P R N N P D N S V A D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P12688 680 76461 S310 L S F D S A A S I R L Y N H H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.7 66.2 97.6 N.A. 96.5 96.9 N.A. 95.3 95.1 88.9 86.6 N.A. 34.7 N.A. 47 62.7
Protein Similarity: 100 70.2 67.1 99 N.A. 98.6 98.6 N.A. 98.3 97.2 94.2 92.8 N.A. 47.9 N.A. 63.5 75
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 93.3 100 80 60 N.A. 6.6 N.A. 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 100 80 80 N.A. 13.3 N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 8 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 8 8 0 8 8 0 15 8 8 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 72 0 72 8 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 8 % H
% Ile: 0 0 0 65 0 0 58 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 % K
% Leu: 15 0 0 8 72 0 8 0 8 0 8 0 0 0 72 % L
% Met: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 0 22 15 8 0 8 0 0 8 0 0 % N
% Pro: 0 8 0 8 0 0 0 8 15 72 0 0 58 0 0 % P
% Gln: 0 79 0 0 8 0 0 0 50 0 72 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 15 0 0 0 0 8 % R
% Ser: 8 8 72 0 8 0 0 72 0 0 15 0 8 0 0 % S
% Thr: 8 0 8 0 0 8 0 8 8 0 0 0 0 0 8 % T
% Val: 72 0 0 0 8 0 0 0 0 0 8 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _