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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK1
All Species:
40.61
Human Site:
T253
Identified Species:
68.72
UniProt:
O00141
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00141
NP_001137148.1
431
48942
T253
E
N
I
E
H
N
S
T
T
S
T
F
C
G
T
Chimpanzee
Pan troglodytes
XP_518751
605
68702
T427
E
N
I
E
H
N
S
T
T
S
T
F
C
G
T
Rhesus Macaque
Macaca mulatta
XP_001102277
637
72261
T459
E
N
I
E
H
N
S
T
T
S
T
F
C
G
T
Dog
Lupus familis
XP_849801
431
48950
T253
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVC6
431
48910
T253
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Rat
Rattus norvegicus
Q06226
430
48909
T253
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507569
431
48976
T253
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Chicken
Gallus gallus
Q6U1I9
432
48872
T254
E
N
I
E
H
N
G
T
T
S
T
F
C
G
T
Frog
Xenopus laevis
Q6GLY8
434
49082
I256
E
N
I
E
P
N
G
I
T
S
T
F
C
G
T
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
T255
E
N
I
E
P
N
G
T
T
S
T
F
C
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
T420
E
D
I
T
Y
G
R
T
T
K
T
F
C
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q2PJ68
463
54273
Q286
G
L
C
K
E
D
M
Q
G
S
K
T
T
S
T
Sea Urchin
Strong. purpuratus
XP_001192139
440
49530
T258
E
G
I
A
A
K
K
T
T
S
T
F
C
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12688
680
76461
K501
L
N
M
K
D
D
D
K
T
D
T
F
C
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.7
66.2
97.6
N.A.
96.5
96.9
N.A.
95.3
95.1
88.9
86.6
N.A.
34.7
N.A.
47
62.7
Protein Similarity:
100
70.2
67.1
99
N.A.
98.6
98.6
N.A.
98.3
97.2
94.2
92.8
N.A.
47.9
N.A.
63.5
75
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
80
86.6
N.A.
60
N.A.
13.3
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
80
86.6
N.A.
73.3
N.A.
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
93
0
0
% C
% Asp:
0
8
0
0
8
15
8
0
0
8
0
0
0
0
0
% D
% Glu:
86
0
0
72
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% F
% Gly:
8
8
0
0
0
8
50
0
8
0
0
0
0
93
0
% G
% His:
0
0
0
0
58
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
86
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
15
0
8
8
8
0
8
8
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
79
0
0
0
72
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
22
0
0
86
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
79
93
0
93
8
8
0
100
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _