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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD9
All Species:
9.09
Human Site:
T375
Identified Species:
18.18
UniProt:
O00144
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00144
NP_003499.1
591
64466
T375
L
K
T
I
V
I
L
T
L
R
K
V
A
G
D
Chimpanzee
Pan troglodytes
XP_527779
484
53212
A273
I
L
T
L
R
K
V
A
G
D
E
L
T
G
L
Rhesus Macaque
Macaca mulatta
XP_001109720
567
63652
V357
V
K
T
I
L
I
L
V
M
R
R
V
A
G
D
Dog
Lupus familis
XP_546927
594
64924
T378
L
K
T
I
V
I
L
T
L
R
K
V
A
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9R216
592
64976
T376
L
K
T
I
V
V
L
T
L
R
K
V
A
G
D
Rat
Rattus norvegicus
Q9QZH0
538
60336
V322
M
A
S
S
I
W
W
V
I
L
T
L
T
W
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520614
537
59681
V327
V
K
T
I
A
I
L
V
M
R
R
V
A
G
D
Chicken
Gallus gallus
Q9PWH2
585
65927
V375
V
K
T
I
M
I
L
V
M
R
R
V
A
G
D
Frog
Xenopus laevis
Q9DEB5
586
65560
V376
V
K
T
I
M
I
L
V
M
R
R
V
A
G
D
Zebra Danio
Brachydanio rerio
NP_571586
577
64904
I367
G
I
P
A
L
K
T
I
V
I
L
T
M
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
A366
A
F
A
W
F
L
A
A
G
L
K
W
G
H
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790565
610
68431
F374
L
K
A
V
I
A
L
F
K
R
R
L
D
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
61.7
96.6
N.A.
95.6
47.8
N.A.
60
63.7
62.9
71.4
N.A.
36.7
N.A.
N.A.
47
Protein Similarity:
100
74.2
75.6
97.3
N.A.
96.7
64.3
N.A.
71.5
78.3
77.5
81.3
N.A.
53.6
N.A.
N.A.
64.2
P-Site Identity:
100
13.3
66.6
100
N.A.
93.3
0
N.A.
66.6
66.6
66.6
0
N.A.
6.6
N.A.
N.A.
33.3
P-Site Similarity:
100
46.6
93.3
100
N.A.
100
33.3
N.A.
86.6
93.3
93.3
13.3
N.A.
20
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
9
9
9
9
17
0
0
0
0
59
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
67
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% E
% Phe:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
9
0
0
0
0
0
0
0
17
0
0
0
9
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
9
0
59
17
50
0
9
9
9
0
0
0
0
0
% I
% Lys:
0
67
0
0
0
17
0
0
9
0
34
0
0
0
9
% K
% Leu:
34
9
0
9
17
9
67
0
25
17
9
25
0
0
9
% L
% Met:
9
0
0
0
17
0
0
0
34
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
67
42
0
0
9
0
% R
% Ser:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
67
0
0
0
9
25
0
0
9
9
17
0
0
% T
% Val:
34
0
0
9
25
9
9
42
9
0
0
59
0
0
0
% V
% Trp:
0
0
0
9
0
9
9
0
0
0
0
9
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _