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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD9 All Species: 26.36
Human Site: T433 Identified Species: 52.73
UniProt: O00144 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00144 NP_003499.1 591 64466 T433 H I R K I M K T G G T N T E K
Chimpanzee Pan troglodytes XP_527779 484 53212 T331 M K T G G T N T E K L E K L M
Rhesus Macaque Macaca mulatta XP_001109720 567 63652 T415 H I R R V M K T G G E N T D K
Dog Lupus familis XP_546927 594 64924 T436 H I R K I M K T G G T N T E K
Cat Felis silvestris
Mouse Mus musculus Q9R216 592 64976 T434 H I R K I M K T G G T N T E K
Rat Rattus norvegicus Q9QZH0 538 60336 V380 E L T G L C Y V G N Q S L D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520614 537 59681 T385 H I R R V M K T G G E N T D K
Chicken Gallus gallus Q9PWH2 585 65927 T433 H I R R V M K T G G E N T D K
Frog Xenopus laevis Q9DEB5 586 65560 T434 H I R R V M K T G G E N T D K
Zebra Danio Brachydanio rerio NP_571586 577 64904 K425 V A L F H I R K V M K T E G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18537 581 64829 A424 L D T H S L G A F L I L P L C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790565 610 68431 N432 R I R K V M K N G G T N I D K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 61.7 96.6 N.A. 95.6 47.8 N.A. 60 63.7 62.9 71.4 N.A. 36.7 N.A. N.A. 47
Protein Similarity: 100 74.2 75.6 97.3 N.A. 96.7 64.3 N.A. 71.5 78.3 77.5 81.3 N.A. 53.6 N.A. N.A. 64.2
P-Site Identity: 100 6.6 73.3 100 N.A. 100 6.6 N.A. 73.3 73.3 73.3 0 N.A. 0 N.A. N.A. 66.6
P-Site Similarity: 100 6.6 93.3 100 N.A. 100 33.3 N.A. 93.3 93.3 93.3 13.3 N.A. 6.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 50 0 % D
% Glu: 9 0 0 0 0 0 0 0 9 0 34 9 9 25 0 % E
% Phe: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 0 0 17 9 0 9 0 75 67 0 0 0 9 0 % G
% His: 59 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 67 0 0 25 9 0 0 0 0 9 0 9 0 0 % I
% Lys: 0 9 0 34 0 0 67 9 0 9 9 0 9 0 67 % K
% Leu: 9 9 9 0 9 9 0 0 0 9 9 9 9 17 0 % L
% Met: 9 0 0 0 0 67 0 0 0 9 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 9 9 0 9 0 67 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 9 0 67 34 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % S
% Thr: 0 0 25 0 0 9 0 67 0 0 34 9 59 0 9 % T
% Val: 9 0 0 0 42 0 0 9 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _