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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZD9 All Species: 36.67
Human Site: Y262 Identified Species: 73.33
UniProt: O00144 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00144 NP_003499.1 591 64466 Y262 L E P H R F Q Y P E R P I I F
Chimpanzee Pan troglodytes XP_527779 484 53212 S164 E R P I I F L S M C Y N V Y S
Rhesus Macaque Macaca mulatta XP_001109720 567 63652 Y244 I D P A R F R Y P E R P I I F
Dog Lupus familis XP_546927 594 64924 Y265 L E P H R F Q Y P E R P I I F
Cat Felis silvestris
Mouse Mus musculus Q9R216 592 64976 Y263 L E P H R F Q Y P E R P I I F
Rat Rattus norvegicus Q9QZH0 538 60336 T187 E E C H S V G T N S D Q Y I W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520614 537 59681 Y214 V D P A R F R Y P E R P I V F
Chicken Gallus gallus Q9PWH2 585 65927 Y262 I D P Q R F K Y P E R P I I F
Frog Xenopus laevis Q9DEB5 586 65560 Y263 V D P L R F K Y P E R P I I F
Zebra Danio Brachydanio rerio NP_571586 577 64904 Y258 L D P H R F Q Y P E R P I I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18537 581 64829 V256 W V G S W A A V C V A S C L F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790565 610 68431 Y260 I D R G R F K Y P E R P I I F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 61.7 96.6 N.A. 95.6 47.8 N.A. 60 63.7 62.9 71.4 N.A. 36.7 N.A. N.A. 47
Protein Similarity: 100 74.2 75.6 97.3 N.A. 96.7 64.3 N.A. 71.5 78.3 77.5 81.3 N.A. 53.6 N.A. N.A. 64.2
P-Site Identity: 100 13.3 73.3 100 N.A. 100 20 N.A. 66.6 73.3 73.3 93.3 N.A. 6.6 N.A. N.A. 66.6
P-Site Similarity: 100 20 93.3 100 N.A. 100 26.6 N.A. 93.3 93.3 93.3 100 N.A. 13.3 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 9 9 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 9 9 0 0 9 0 0 % C
% Asp: 0 50 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 17 34 0 0 0 0 0 0 0 75 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 84 0 0 0 0 0 0 0 0 84 % F
% Gly: 0 0 9 9 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 25 0 0 9 9 0 0 0 0 0 0 0 75 75 0 % I
% Lys: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % K
% Leu: 34 0 0 9 0 0 9 0 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % N
% Pro: 0 0 75 0 0 0 0 0 75 0 0 75 0 0 0 % P
% Gln: 0 0 0 9 0 0 34 0 0 0 0 9 0 0 0 % Q
% Arg: 0 9 9 0 75 0 17 0 0 0 75 0 0 0 0 % R
% Ser: 0 0 0 9 9 0 0 9 0 9 0 9 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 17 9 0 0 0 9 0 9 0 9 0 0 9 9 0 % V
% Trp: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 9 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _