Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX39 All Species: 0
Human Site: S129 Identified Species: 0
UniProt: O00148 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00148 NP_005795.2 427 49130 S129 R E L A F Q I S K E Y E R F S
Chimpanzee Pan troglodytes XP_001171771 416 46980
Rhesus Macaque Macaca mulatta XP_001112060 544 61883
Dog Lupus familis XP_533895 427 49073
Cat Felis silvestris
Mouse Mus musculus Q8VDW0 427 49049
Rat Rattus norvegicus Q5U216 427 49091
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515366 430 49724
Chicken Gallus gallus Q5ZHZ0 428 48985
Frog Xenopus laevis NP_001079623 427 49158
Zebra Danio Brachydanio rerio NP_998142 427 48929
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27268 424 48633
Honey Bee Apis mellifera XP_624894 424 48776
Nematode Worm Caenorhab. elegans Q18212 425 48474
Sea Urchin Strong. purpuratus XP_779919 429 49042
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFN6 427 48319
Baker's Yeast Sacchar. cerevisiae Q07478 446 50290
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.9 76.2 97.8 N.A. 97.1 96.7 N.A. 76.5 89.9 90.4 91.8 N.A. 82.1 82.4 75.8 82.2
Protein Similarity: 100 89.9 76.4 99.5 N.A. 99.7 99.5 N.A. 89.5 96.7 96.4 97.1 N.A. 91.8 91.5 87.5 90.9
P-Site Identity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 0 0 0
P-Site Similarity: 100 0 0 0 N.A. 0 0 N.A. 0 0 0 0 N.A. 0 0 0 0
Percent
Protein Identity: N.A. N.A. N.A. 70.4 62.1 N.A.
Protein Similarity: N.A. N.A. N.A. 84.3 78 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 100 0 0 0 0 0 0 0 100 0 100 0 0 0 % E
% Phe: 0 0 0 0 100 0 0 0 0 0 0 0 0 100 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % Q
% Arg: 100 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 100 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _