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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX39 All Species: 24.85
Human Site: T26 Identified Species: 36.44
UniProt: O00148 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00148 NP_005795.2 427 49130 T26 P Q A P Q E S T P A P P K K D
Chimpanzee Pan troglodytes XP_001171771 416 46980 T26 P Q A P Q E S T P A P P K K D
Rhesus Macaque Macaca mulatta XP_001112060 544 61883 T154 P Q A P Q E S T P A P P K K D
Dog Lupus familis XP_533895 427 49073 T26 P Q A P P E S T P A P P K K D
Cat Felis silvestris
Mouse Mus musculus Q8VDW0 427 49049 T26 P Q A P Q E S T P A P P K K D
Rat Rattus norvegicus Q5U216 427 49091 T26 P Q V P Q E S T P A P P K K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515366 430 49724 L26 F E N M E T E L P S P V K K S
Chicken Gallus gallus Q5ZHZ0 428 48985 S27 N A A G G D G S E A P P K K D
Frog Xenopus laevis NP_001079623 427 49158 A26 P Q A P A E T A V P I A R K E
Zebra Danio Brachydanio rerio NP_998142 427 48929 A26 P Q G A P E S A A P V G K K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27268 424 48633 N23 T E T T A V E N Q E A P K K D
Honey Bee Apis mellifera XP_624894 424 48776 R24 E Q L V D G S R D T P A K K E
Nematode Worm Caenorhab. elegans Q18212 425 48474 V23 I Q D K Q P E V G G G D A R K
Sea Urchin Strong. purpuratus XP_779919 429 49042 A29 T A D A G G D A V K Q Q K E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LFN6 427 48319 G28 D E K V P D S G N K V N G E A
Baker's Yeast Sacchar. cerevisiae Q07478 446 50290 N44 S A T E G D N N N N T A A G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.9 76.2 97.8 N.A. 97.1 96.7 N.A. 76.5 89.9 90.4 91.8 N.A. 82.1 82.4 75.8 82.2
Protein Similarity: 100 89.9 76.4 99.5 N.A. 99.7 99.5 N.A. 89.5 96.7 96.4 97.1 N.A. 91.8 91.5 87.5 90.9
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 26.6 46.6 40 40 N.A. 26.6 33.3 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 46.6 60 60 46.6 N.A. 33.3 40 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 70.4 62.1 N.A.
Protein Similarity: N.A. N.A. N.A. 84.3 78 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 44 13 13 0 0 19 7 44 7 19 13 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 13 0 7 19 7 0 7 0 0 7 0 0 57 % D
% Glu: 7 19 0 7 7 50 19 0 7 7 0 0 0 13 19 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 7 19 13 7 7 7 7 7 7 7 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 7 7 0 0 0 0 0 13 0 0 75 75 7 % K
% Leu: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 0 0 0 7 13 13 7 0 7 0 0 0 % N
% Pro: 50 0 0 44 19 7 0 0 44 13 57 50 0 0 0 % P
% Gln: 0 63 0 0 38 0 0 0 7 0 7 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 0 0 7 7 0 % R
% Ser: 7 0 0 0 0 0 57 7 0 7 0 0 0 0 7 % S
% Thr: 13 0 13 7 0 7 7 38 0 7 7 0 0 0 7 % T
% Val: 0 0 7 13 0 7 0 7 13 0 13 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _