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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT7
All Species:
17.58
Human Site:
T149
Identified Species:
48.33
UniProt:
O00154
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00154
NP_009205.3
380
41796
T149
V
M
S
E
N
I
L
T
G
A
K
K
L
T
N
Chimpanzee
Pan troglodytes
XP_001156114
380
41861
T149
V
M
S
E
N
I
L
T
G
A
K
K
L
T
N
Rhesus Macaque
Macaca mulatta
XP_001092298
380
41957
T149
V
M
S
E
N
I
L
T
G
A
K
K
L
T
N
Dog
Lupus familis
XP_536727
321
35622
L106
A
T
L
W
Y
V
P
L
S
L
K
N
V
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91V12
381
42518
T150
V
M
S
E
N
I
L
T
G
T
K
K
L
T
N
Rat
Rattus norvegicus
Q64559
381
42717
T150
V
L
S
E
N
I
L
T
G
T
K
K
L
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515016
266
29621
K51
A
E
I
T
Y
T
S
K
H
S
V
E
V
Q
V
Chicken
Gallus gallus
XP_417533
324
35996
K109
L
S
L
K
N
V
N
K
V
V
E
V
P
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001004617
254
27842
H39
G
C
I
I
G
T
R
H
C
N
T
Q
S
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
91.3
83.1
N.A.
88.9
88.4
N.A.
60
66.3
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
93.9
83.6
N.A.
91.8
91.5
N.A.
65.7
73.4
N.A.
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
86.6
N.A.
0
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
20
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% D
% Glu:
0
12
0
56
0
0
0
0
0
0
12
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
12
0
0
0
56
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% H
% Ile:
0
0
23
12
0
56
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
12
0
0
0
23
0
0
67
56
0
0
12
% K
% Leu:
12
12
23
0
0
0
56
12
0
12
0
0
56
0
0
% L
% Met:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
67
0
12
0
0
12
0
12
0
0
56
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
12
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
56
0
0
0
12
0
12
12
0
0
12
0
0
% S
% Thr:
0
12
0
12
0
23
0
56
0
23
12
0
0
56
0
% T
% Val:
56
0
0
0
0
23
0
0
12
12
12
12
23
0
12
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _