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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR25
All Species:
3.64
Human Site:
S196
Identified Species:
8.89
UniProt:
O00155
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00155
NP_005289.2
361
38779
S196
S
Q
C
G
E
E
P
S
H
A
F
Q
G
L
S
Chimpanzee
Pan troglodytes
Q9GLN9
359
41015
E185
T
V
C
A
F
H
Y
E
S
Q
N
S
T
L
P
Rhesus Macaque
Macaca mulatta
O97663
360
40769
P190
C
A
E
K
K
A
T
P
L
K
L
I
W
S
L
Dog
Lupus familis
XP_545069
360
40485
S190
C
A
E
K
R
A
T
S
T
K
L
T
W
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P0C5I1
358
38736
W196
S
Q
C
A
E
E
P
W
E
A
L
Q
G
V
G
Rat
Rattus norvegicus
P29089
359
40893
E185
T
V
C
A
F
H
Y
E
S
Q
N
S
T
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521758
629
66819
S353
S
L
C
G
E
E
A
S
D
A
F
Q
S
L
S
Chicken
Gallus gallus
P79785
359
41202
D185
T
V
C
G
F
R
Y
D
N
N
N
T
T
L
R
Frog
Xenopus laevis
Q2TAD5
363
40901
V193
C
D
L
D
F
S
G
V
S
S
K
E
N
E
N
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
N191
T
S
C
A
M
D
F
N
L
V
V
S
Q
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31
32.6
33.5
N.A.
74.7
32.1
N.A.
40
27.9
32.2
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.6
50.4
50.4
N.A.
81.1
51.5
N.A.
45.9
50.4
50.1
50.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
6.6
N.A.
60
13.3
N.A.
73.3
20
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
6.6
N.A.
66.6
20
N.A.
73.3
33.3
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
40
0
20
10
0
0
30
0
0
0
10
0
% A
% Cys:
30
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
10
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
30
30
0
20
10
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
40
0
10
0
0
0
20
0
0
0
0
% F
% Gly:
0
0
0
30
0
0
10
0
0
0
0
0
20
0
20
% G
% His:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
20
10
0
0
0
0
20
10
0
0
0
0
% K
% Leu:
0
10
10
0
0
0
0
0
20
0
30
0
0
50
20
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
10
30
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
20
10
0
0
0
0
0
10
20
% P
% Gln:
0
20
0
0
0
0
0
0
0
20
0
30
10
0
0
% Q
% Arg:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
30
10
0
0
0
10
0
30
30
10
0
30
10
10
20
% S
% Thr:
40
0
0
0
0
0
20
0
10
0
0
20
30
0
0
% T
% Val:
0
30
0
0
0
0
0
10
0
10
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
20
0
0
% W
% Tyr:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _