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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR25
All Species:
9.09
Human Site:
S335
Identified Species:
22.22
UniProt:
O00155
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00155
NP_005289.2
361
38779
S335
R
L
A
R
R
I
S
S
A
S
S
L
S
R
D
Chimpanzee
Pan troglodytes
Q9GLN9
359
41015
L330
K
A
K
S
H
S
N
L
S
T
K
M
S
T
L
Rhesus Macaque
Macaca mulatta
O97663
360
40769
T330
N
Y
D
F
G
S
S
T
E
T
S
D
S
H
L
Dog
Lupus familis
XP_545069
360
40485
S330
N
Y
D
F
G
S
S
S
E
T
L
D
S
H
L
Cat
Felis silvestris
Mouse
Mus musculus
P0C5I1
358
38736
S332
R
Q
V
R
R
I
S
S
A
S
S
L
S
R
D
Rat
Rattus norvegicus
P29089
359
40893
L330
T
A
K
S
H
A
G
L
S
T
K
M
S
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521758
629
66819
S492
R
L
V
R
R
A
S
S
V
S
S
S
R
D
S
Chicken
Gallus gallus
P79785
359
41202
L330
N
V
S
T
H
P
S
L
T
T
K
M
S
S
L
Frog
Xenopus laevis
Q2TAD5
363
40901
L336
F
F
G
F
K
K
V
L
Q
G
H
L
S
N
T
Zebra Danio
Brachydanio rerio
A0T2N3
359
40129
K334
C
L
C
L
L
N
L
K
K
A
L
H
A
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31
32.6
33.5
N.A.
74.7
32.1
N.A.
40
27.9
32.2
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.6
50.4
50.4
N.A.
81.1
51.5
N.A.
45.9
50.4
50.1
50.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
20
20
N.A.
86.6
6.6
N.A.
53.3
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
33.3
26.6
N.A.
86.6
26.6
N.A.
53.3
40
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
10
0
0
20
0
0
20
10
0
0
10
0
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
0
0
0
0
0
20
0
10
20
% D
% Glu:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% E
% Phe:
10
10
0
30
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
20
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
30
0
0
0
0
0
10
10
0
20
0
% H
% Ile:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
20
0
10
10
0
10
10
0
30
0
0
0
0
% K
% Leu:
0
30
0
10
10
0
10
40
0
0
20
30
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% M
% Asn:
30
0
0
0
0
10
10
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
30
0
0
30
30
0
0
0
0
0
0
0
10
20
0
% R
% Ser:
0
0
10
20
0
30
60
40
20
30
40
10
80
20
10
% S
% Thr:
10
0
0
10
0
0
0
10
10
50
0
0
0
20
10
% T
% Val:
0
10
20
0
0
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _