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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR25 All Species: 10.91
Human Site: S344 Identified Species: 26.67
UniProt: O00155 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00155 NP_005289.2 361 38779 S344 S S L S R D D S S V F R C R A
Chimpanzee Pan troglodytes Q9GLN9 359 41015 Y339 T K M S T L S Y R P S D N V S
Rhesus Macaque Macaca mulatta O97663 360 40769 K339 T S D S H L T K A L S T F I H
Dog Lupus familis XP_545069 360 40485 K339 T L D S H L T K A L S N F I H
Cat Felis silvestris
Mouse Mus musculus P0C5I1 358 38736 S341 S S L S R D D S S V F R G R S
Rat Rattus norvegicus P29089 359 40893 Y339 T K M S T L S Y R P S D N M S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521758 629 66819 D501 S S S R D S R D S G S L F Q A
Chicken Gallus gallus P79785 359 41202 Y339 T K M S S L S Y R P P E N I R
Frog Xenopus laevis Q2TAD5 363 40901 S345 G H L S N T S S S L S A Q T Q
Zebra Danio Brachydanio rerio A0T2N3 359 40129 S343 A L H A S P A S S L S S Q K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 31 32.6 33.5 N.A. 74.7 32.1 N.A. 40 27.9 32.2 31.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 50.6 50.4 50.4 N.A. 81.1 51.5 N.A. 45.9 50.4 50.1 50.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 13.3 6.6 N.A. 86.6 6.6 N.A. 26.6 6.6 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 33.3 26.6 N.A. 93.3 26.6 N.A. 33.3 20 33.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 10 0 20 0 0 10 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 20 0 10 20 20 10 0 0 0 20 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 20 0 30 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % G
% His: 0 10 10 0 20 0 0 0 0 0 0 0 0 0 20 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % I
% Lys: 0 30 0 0 0 0 0 20 0 0 0 0 0 10 0 % K
% Leu: 0 20 30 0 0 50 0 0 0 40 0 10 0 0 0 % L
% Met: 0 0 30 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 10 30 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 30 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 20 10 10 % Q
% Arg: 0 0 0 10 20 0 10 0 30 0 0 20 0 20 10 % R
% Ser: 30 40 10 80 20 10 40 40 50 0 70 10 0 0 30 % S
% Thr: 50 0 0 0 20 10 20 0 0 0 0 10 0 10 10 % T
% Val: 0 0 0 0 0 0 0 0 0 20 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _