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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1C
All Species:
14.85
Human Site:
T453
Identified Species:
27.22
UniProt:
O00159
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00159
NP_001074248.1
1063
121724
T453
Q
Q
L
F
I
E
L
T
L
K
S
E
Q
E
E
Chimpanzee
Pan troglodytes
XP_001174155
1044
119627
T451
Q
Q
L
F
I
E
L
T
L
K
S
E
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001117297
943
107150
L385
S
T
T
V
L
G
L
L
D
I
Y
G
F
E
V
Dog
Lupus familis
XP_537765
1636
184093
T582
Q
Q
L
F
I
E
L
T
L
K
S
E
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTI7
1063
121926
T453
Q
Q
L
F
I
E
L
T
L
K
S
E
Q
E
E
Rat
Rattus norvegicus
Q63355
1044
119793
S437
F
I
E
L
T
L
K
S
E
Q
E
E
Y
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508359
1162
132441
A474
L
I
E
M
T
L
K
A
E
Q
E
E
Y
E
M
Chicken
Gallus gallus
Q5ZLA6
1028
118889
V436
E
G
I
A
W
E
P
V
Q
Y
F
N
N
K
I
Frog
Xenopus laevis
A0MP03
1028
118817
V436
E
G
I
A
W
E
P
V
Q
Y
F
N
N
K
I
Zebra Danio
Brachydanio rerio
A5PF48
1026
118045
E436
A
E
G
W
E
R
V
E
Y
F
N
N
K
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23979
1035
118971
E437
E
Y
R
R
E
G
I
E
W
I
P
V
E
Y
F
Honey Bee
Apis mellifera
XP_394436
1060
122678
E449
I
Q
L
T
L
K
S
E
Q
E
E
Y
L
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
Q447
Q
L
T
L
K
A
E
Q
D
E
Y
A
R
E
Q
Conservation
Percent
Protein Identity:
100
95.6
84.2
63.2
N.A.
96.9
95
N.A.
56.6
80.1
75.2
65.9
N.A.
50.7
52.1
N.A.
N.A.
Protein Similarity:
100
96.2
85.2
64.1
N.A.
98.8
96.9
N.A.
71.3
89.4
86.6
81.1
N.A.
66.7
69.9
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
13.3
N.A.
13.3
6.6
6.6
0
N.A.
0
20
N.A.
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
26.6
N.A.
20
26.6
26.6
33.3
N.A.
20
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
8
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% D
% Glu:
24
8
16
0
16
47
8
24
16
16
24
47
8
62
39
% E
% Phe:
8
0
0
31
0
0
0
0
0
8
16
0
8
0
8
% F
% Gly:
0
16
8
0
0
16
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
16
0
31
0
8
0
0
16
0
0
0
8
24
% I
% Lys:
0
0
0
0
8
8
16
0
0
31
0
0
8
16
0
% K
% Leu:
8
8
39
16
16
16
39
8
31
0
0
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
24
16
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
0
8
0
0
0
0
% P
% Gln:
39
39
0
0
0
0
0
8
24
16
0
0
31
0
8
% Q
% Arg:
0
0
8
8
0
8
0
0
0
0
0
0
8
8
0
% R
% Ser:
8
0
0
0
0
0
8
8
0
0
31
0
0
0
0
% S
% Thr:
0
8
16
8
16
0
0
31
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
16
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
8
16
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
16
16
8
16
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _