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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXYD1
All Species:
18.18
Human Site:
S88
Identified Species:
44.44
UniProt:
O00168
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00168
NP_005022.2
92
10441
S88
R
S
S
I
R
R
L
S
T
R
R
R
_
_
_
Chimpanzee
Pan troglodytes
XP_508784
107
11689
E101
L
I
T
A
N
A
T
E
P
Q
K
A
E
N
_
Rhesus Macaque
Macaca mulatta
XP_001117816
60
6961
Dog
Lupus familis
XP_533697
92
10512
S88
R
S
S
I
R
R
L
S
T
R
R
R
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z239
92
10304
S88
R
S
S
I
R
R
L
S
S
R
R
R
_
_
_
Rat
Rattus norvegicus
O08589
92
10347
S88
R
S
S
I
R
R
L
S
T
R
R
R
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519862
78
8988
S74
R
S
S
I
R
R
L
S
S
R
R
R
_
_
_
Chicken
Gallus gallus
NP_001074348
95
10193
G89
L
I
T
S
N
A
T
G
A
Q
K
A
E
N
_
Frog
Xenopus laevis
O13001
61
6981
Zebra Danio
Brachydanio rerio
NP_956141
99
10728
E93
L
M
V
S
K
T
K
E
T
P
T
A
E
N
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
63
90.2
N.A.
82.6
83.6
N.A.
68.4
42.1
27.1
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57
65.2
94.5
N.A.
91.3
92.3
N.A.
76
63.1
44.5
54.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
91.6
100
N.A.
91.6
0
0
7.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
21.4
0
100
N.A.
100
100
N.A.
100
21.4
0
14.2
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
20
0
0
10
0
0
30
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
20
0
0
0
0
30
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
50
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
10
0
0
0
20
0
0
0
0
% K
% Leu:
30
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
0
0
30
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
50
0
0
0
50
50
0
0
0
50
50
50
0
0
0
% R
% Ser:
0
50
50
20
0
0
0
50
20
0
0
0
0
0
0
% S
% Thr:
0
0
20
0
0
10
20
0
40
0
10
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
50
50
80
% _