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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIP
All Species:
25.76
Human Site:
S220
Identified Species:
47.22
UniProt:
O00170
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00170
NP_003968.2
330
37636
S220
Q
M
K
E
Q
P
G
S
P
E
W
I
Q
L
D
Chimpanzee
Pan troglodytes
XP_508597
330
37676
S220
Q
M
K
E
Q
P
G
S
P
E
W
I
Q
L
D
Rhesus Macaque
Macaca mulatta
Q95MP0
392
44712
E219
Q
T
K
E
K
P
W
E
V
Q
W
L
K
L
E
Dog
Lupus familis
XP_851841
330
37527
S220
Q
M
K
E
Q
P
G
S
P
D
W
I
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O08915
330
37586
S220
Q
M
K
E
Q
P
G
S
P
D
W
I
Q
L
D
Rat
Rattus norvegicus
Q5FWY5
330
37580
S220
Q
M
K
E
Q
P
G
S
P
D
W
I
Q
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511228
535
60618
E200
Q
T
K
E
K
A
W
E
A
P
W
L
K
L
E
Chicken
Gallus gallus
NP_989800
327
37490
S217
Q
M
K
E
Q
P
G
S
P
D
W
I
E
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922877
342
38330
D221
Q
M
K
E
R
P
G
D
E
H
W
I
K
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
C320
H
F
E
A
K
Q
E
C
N
E
V
L
A
L
D
Honey Bee
Apis mellifera
XP_623137
318
36854
E209
M
L
G
E
K
P
N
E
E
E
W
L
A
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788955
328
37407
S218
L
L
H
E
K
P
N
S
S
E
W
L
D
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDC0
365
41787
G219
D
F
M
F
Q
L
Y
G
K
Y
Q
D
M
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
41.3
94.5
N.A.
94.2
93.9
N.A.
32.7
79
N.A.
64.6
N.A.
20.5
41.5
N.A.
44.2
Protein Similarity:
100
99.6
59.4
97.2
N.A.
97.8
97.2
N.A.
43.9
87.2
N.A.
79.2
N.A.
36.2
62.7
N.A.
66
P-Site Identity:
100
100
40
93.3
N.A.
93.3
93.3
N.A.
33.3
86.6
N.A.
66.6
N.A.
20
33.3
N.A.
46.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
60
100
N.A.
80
N.A.
40
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
8
0
0
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
31
0
8
8
0
70
% D
% Glu:
0
0
8
85
0
0
8
24
16
39
0
0
8
0
16
% E
% Phe:
0
16
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
54
8
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% I
% Lys:
0
0
70
0
39
0
0
0
8
0
0
0
24
0
0
% K
% Leu:
8
16
0
0
0
8
0
0
0
0
0
39
0
93
8
% L
% Met:
8
54
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
16
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
77
0
0
47
8
0
0
0
0
0
% P
% Gln:
70
0
0
0
54
8
0
0
0
8
8
0
39
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
54
8
0
0
0
0
0
0
% S
% Thr:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
16
0
0
0
85
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _