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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK1
All Species:
15.45
Human Site:
S4
Identified Species:
34
UniProt:
O00180
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00180
NP_002236.1
336
38143
S4
_
_
_
_
M
L
Q
S
L
A
G
S
S
C
V
Chimpanzee
Pan troglodytes
XP_524250
313
33801
Rhesus Macaque
Macaca mulatta
XP_001112053
396
44876
S64
E
G
K
Q
G
L
R
S
R
T
G
K
G
V
V
Dog
Lupus familis
XP_546083
304
34173
Cat
Felis silvestris
Mouse
Mus musculus
O08581
336
38257
S4
_
_
_
_
M
L
Q
S
L
A
G
S
S
C
V
Rat
Rattus norvegicus
Q9Z2T2
336
38210
S4
_
_
_
_
M
L
Q
S
L
A
G
S
S
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512651
250
28124
Chicken
Gallus gallus
XP_419561
336
38076
S4
_
_
_
_
M
L
Q
S
L
A
G
S
S
C
V
Frog
Xenopus laevis
Q63ZI0
374
42700
A28
V
G
A
A
V
F
D
A
L
E
S
D
Y
E
M
Zebra Danio
Brachydanio rerio
NP_001092223
338
38478
C4
_
_
_
_
M
L
Q
C
L
S
G
S
S
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
N5
_
_
_
M
K
R
Q
N
I
R
T
L
S
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
81.5
65.4
N.A.
94
96.4
N.A.
57.1
89.8
28.6
69.2
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
100
58.9
82.8
73.5
N.A.
97
98.2
N.A.
62.7
94.6
46.2
84.6
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
100
0
26.6
0
N.A.
100
100
N.A.
0
100
6.6
72.7
N.A.
N.A.
N.A.
16.6
N.A.
P-Site Similarity:
100
0
40
0
N.A.
100
100
N.A.
0
100
33.3
90.9
N.A.
N.A.
N.A.
41.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
10
0
37
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
46
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
10
0
0
0
0
0
55
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
0
10
0
10
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
55
0
0
55
0
0
10
0
10
0
% L
% Met:
0
0
0
10
46
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
55
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
46
0
10
10
46
55
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
55
55
55
46
0
0
0
0
0
0
0
0
0
0
0
% _