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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK1
All Species:
22.73
Human Site:
Y231
Identified Species:
50
UniProt:
O00180
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00180
NP_002236.1
336
38143
Y231
S
T
I
G
L
G
D
Y
V
P
G
E
G
Y
N
Chimpanzee
Pan troglodytes
XP_524250
313
33801
G218
S
L
S
T
I
G
L
G
D
Y
V
P
G
E
A
Rhesus Macaque
Macaca mulatta
XP_001112053
396
44876
Y291
S
T
I
G
L
G
D
Y
V
P
G
E
G
Y
N
Dog
Lupus familis
XP_546083
304
34173
F209
G
E
G
Y
N
Q
K
F
R
E
L
Y
K
I
G
Cat
Felis silvestris
Mouse
Mus musculus
O08581
336
38257
Y231
S
T
I
G
L
G
D
Y
V
P
G
E
G
Y
N
Rat
Rattus norvegicus
Q9Z2T2
336
38210
Y231
S
T
I
G
L
G
D
Y
V
P
G
E
G
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512651
250
28124
R155
E
G
Y
N
Q
K
F
R
E
L
Y
K
I
G
I
Chicken
Gallus gallus
XP_419561
336
38076
Y231
S
T
I
G
L
G
D
Y
V
P
G
E
G
Y
N
Frog
Xenopus laevis
Q63ZI0
374
42700
E260
D
E
R
R
D
A
E
E
R
A
S
L
A
G
N
Zebra Danio
Brachydanio rerio
NP_001092223
338
38478
Y231
S
T
I
G
L
G
D
Y
V
P
G
E
G
Y
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
V225
E
Y
V
F
F
S
L
V
F
I
L
F
G
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
81.5
65.4
N.A.
94
96.4
N.A.
57.1
89.8
28.6
69.2
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
100
58.9
82.8
73.5
N.A.
97
98.2
N.A.
62.7
94.6
46.2
84.6
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
100
20
100
0
N.A.
100
100
N.A.
0
100
6.6
93.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
6.6
N.A.
100
100
N.A.
6.6
100
13.3
100
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
55
0
10
0
0
0
0
0
0
% D
% Glu:
19
19
0
0
0
0
10
10
10
10
0
55
0
10
0
% E
% Phe:
0
0
0
10
10
0
10
10
10
0
0
10
0
0
0
% F
% Gly:
10
10
10
55
0
64
0
10
0
0
55
0
73
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
55
0
10
0
0
0
0
10
0
0
10
10
10
% I
% Lys:
0
0
0
0
0
10
10
0
0
0
0
10
10
0
0
% K
% Leu:
0
10
0
0
55
0
19
0
0
10
19
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
55
% N
% Pro:
0
0
0
0
0
0
0
0
0
55
0
10
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
10
19
0
0
0
0
0
0
% R
% Ser:
64
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
55
0
10
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
10
55
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
10
0
0
0
55
0
10
10
10
0
55
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _