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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGALS9
All Species:
4.55
Human Site:
S250
Identified Species:
11.11
UniProt:
O00182
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00182
NP_002299.2
355
39518
S250
L
S
G
T
V
L
P
S
A
Q
R
F
H
I
N
Chimpanzee
Pan troglodytes
XP_001156690
355
39458
S250
L
S
G
T
V
L
P
S
A
Q
R
F
H
I
N
Rhesus Macaque
Macaca mulatta
XP_001109730
166
18392
V75
S
T
P
A
L
P
P
V
M
Y
P
H
P
A
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08573
353
40017
D248
I
S
G
N
V
L
P
D
A
T
R
F
H
I
N
Rat
Rattus norvegicus
P97840
354
39927
D249
I
S
G
V
V
L
P
D
A
K
R
F
H
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517844
212
23619
I121
P
F
H
R
V
D
T
I
N
V
Q
G
S
V
R
Chicken
Gallus gallus
Q5ZHQ2
171
19026
A80
G
E
S
E
D
P
P
A
D
V
A
I
E
L
K
Frog
Xenopus laevis
Q6DDR8
171
19215
A80
G
D
S
E
D
P
A
A
D
I
A
I
E
L
R
Zebra Danio
Brachydanio rerio
Q1ECW6
164
18441
A73
I
S
L
T
C
G
C
A
D
V
A
L
D
M
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P36573
279
31791
G188
V
N
L
L
R
K
N
G
D
I
S
F
H
F
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
43.3
N.A.
N.A.
69.5
72.1
N.A.
36
21.1
22.2
20.2
N.A.
N.A.
N.A.
29
N.A.
Protein Similarity:
100
95.7
45.3
N.A.
N.A.
80.5
81.1
N.A.
45.6
31.8
31.5
30.9
N.A.
N.A.
N.A.
46.2
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
73.3
73.3
N.A.
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
80
86.6
N.A.
20
20
13.3
33.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
30
40
0
30
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
20
10
0
20
40
0
0
0
10
0
0
% D
% Glu:
0
10
0
20
0
0
0
0
0
0
0
0
20
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
50
0
10
0
% F
% Gly:
20
0
40
0
0
10
0
10
0
0
0
10
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
10
50
0
0
% H
% Ile:
30
0
0
0
0
0
0
10
0
20
0
20
0
40
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% K
% Leu:
20
0
20
10
10
40
0
0
0
0
0
10
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
10
0
10
0
0
10
0
10
0
0
0
0
0
50
% N
% Pro:
10
0
10
0
0
30
60
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
10
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
40
0
0
0
20
% R
% Ser:
10
50
20
0
0
0
0
20
0
0
10
0
10
0
0
% S
% Thr:
0
10
0
30
0
0
10
0
0
10
0
0
0
0
0
% T
% Val:
10
0
0
10
50
0
0
10
0
30
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _