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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP3
All Species:
30
Human Site:
S313
Identified Species:
50.77
UniProt:
O00186
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00186
NP_009200.2
592
67764
S313
K
L
M
K
E
I
S
S
T
K
K
A
T
E
G
Chimpanzee
Pan troglodytes
XP_001145368
592
67778
S313
K
L
M
K
E
I
S
S
T
K
K
A
T
E
G
Rhesus Macaque
Macaca mulatta
XP_001087621
798
89892
S519
K
L
M
K
E
I
S
S
T
K
K
A
T
E
G
Dog
Lupus familis
XP_547249
592
67727
S313
K
L
M
K
E
I
S
S
T
K
K
A
T
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60770
592
67924
S313
K
L
M
K
E
I
S
S
T
K
K
A
T
E
G
Rat
Rattus norvegicus
P61765
594
67550
S313
S
L
K
D
F
S
S
S
K
R
M
N
T
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
S299
S
L
K
D
F
S
S
S
K
R
M
N
T
G
E
Chicken
Gallus gallus
Q6R748
594
67454
S313
S
L
K
E
F
S
S
S
K
R
M
N
T
G
D
Frog
Xenopus laevis
NP_001090087
589
67497
S313
K
L
V
K
E
I
S
S
S
K
K
E
T
E
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
S322
N
L
K
K
F
T
D
S
K
R
M
G
S
A
D
Honey Bee
Apis mellifera
XP_396375
585
66573
S310
N
L
K
K
F
T
E
S
K
R
M
P
Q
G
D
Nematode Worm
Caenorhab. elegans
P34815
673
76715
K394
L
K
K
F
S
E
S
K
G
N
K
G
T
M
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
A343
N
F
V
S
K
N
K
A
A
Q
L
K
H
S
S
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
A334
G
R
I
K
E
L
I
A
K
N
P
L
L
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
73
94.7
N.A.
91.8
51.3
N.A.
49.6
51.5
67.5
N.A.
N.A.
43.2
44.9
39.6
N.A.
Protein Similarity:
100
100
73.9
96.9
N.A.
96.1
74
N.A.
72.1
73.9
82.7
N.A.
N.A.
67
68.9
60.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
26.6
26.6
80
N.A.
N.A.
20
20
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
33.3
40
93.3
N.A.
N.A.
33.3
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.4
42.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
8
0
0
36
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
8
0
0
0
0
0
0
0
36
% D
% Glu:
0
0
0
8
50
8
8
0
0
0
0
8
0
43
15
% E
% Phe:
0
8
0
8
36
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
15
0
29
43
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
0
0
43
8
0
0
0
0
0
0
0
0
% I
% Lys:
43
8
43
65
8
0
8
8
43
43
50
8
0
0
0
% K
% Leu:
8
79
0
0
0
8
0
0
0
0
8
8
8
0
0
% L
% Met:
0
0
36
0
0
0
0
0
0
0
36
0
0
8
0
% M
% Asn:
22
0
0
0
0
8
0
0
0
15
0
22
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
36
0
0
0
0
0
% R
% Ser:
22
0
0
8
8
22
72
79
8
0
0
0
8
8
8
% S
% Thr:
0
0
0
0
0
15
0
0
36
0
0
0
72
0
0
% T
% Val:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _