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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP3
All Species:
26.06
Human Site:
S542
Identified Species:
44.1
UniProt:
O00186
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00186
NP_009200.2
592
67764
S542
V
I
G
G
I
T
Y
S
E
V
R
C
A
Y
E
Chimpanzee
Pan troglodytes
XP_001145368
592
67778
S542
V
I
G
G
I
T
Y
S
E
M
R
C
A
Y
E
Rhesus Macaque
Macaca mulatta
XP_001087621
798
89892
S748
V
I
G
G
I
T
Y
S
E
M
R
C
A
Y
E
Dog
Lupus familis
XP_547249
592
67727
S542
V
I
G
G
I
T
Y
S
E
M
R
C
A
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60770
592
67924
S543
V
I
G
G
I
T
Y
S
E
M
R
C
A
Y
E
Rat
Rattus norvegicus
P61765
594
67550
N548
I
L
G
G
V
S
L
N
E
M
R
C
A
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
N534
I
L
G
G
V
S
L
N
E
M
R
C
A
Y
E
Chicken
Gallus gallus
Q6R748
594
67454
N548
I
L
G
G
V
S
L
N
E
M
R
C
A
Y
E
Frog
Xenopus laevis
NP_001090087
589
67497
S542
V
I
G
G
I
T
Y
S
E
I
R
C
A
Y
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
V550
P
R
L
I
V
F
I
V
G
G
V
S
M
S
E
Honey Bee
Apis mellifera
XP_396375
585
66573
V540
P
R
L
I
V
F
V
V
G
G
V
C
F
S
E
Nematode Worm
Caenorhab. elegans
P34815
673
76715
V627
I
I
Y
I
I
G
G
V
T
F
S
E
M
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
S613
I
V
G
G
A
T
R
S
E
L
R
V
C
H
K
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
P603
V
I
G
G
I
S
I
P
E
I
K
A
A
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
73
94.7
N.A.
91.8
51.3
N.A.
49.6
51.5
67.5
N.A.
N.A.
43.2
44.9
39.6
N.A.
Protein Similarity:
100
100
73.9
96.9
N.A.
96.1
74
N.A.
72.1
73.9
82.7
N.A.
N.A.
67
68.9
60.7
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
53.3
N.A.
53.3
53.3
93.3
N.A.
N.A.
6.6
13.3
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
93.3
100
N.A.
N.A.
13.3
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.4
42.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
8
72
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
72
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
79
0
0
8
0
0
79
% E
% Phe:
0
0
0
0
0
15
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
79
79
0
8
8
0
15
15
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
36
58
0
22
58
0
15
0
0
15
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% K
% Leu:
0
22
15
0
0
0
22
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
50
0
0
15
0
0
% M
% Asn:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
8
0
0
0
72
0
0
8
0
% R
% Ser:
0
0
0
0
0
29
0
50
0
0
8
8
0
15
0
% S
% Thr:
0
0
0
0
0
50
0
0
8
0
0
0
0
0
0
% T
% Val:
50
8
0
0
36
0
8
22
0
8
15
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
43
0
0
0
0
0
0
72
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _