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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STXBP3 All Species: 18.78
Human Site: S587 Identified Species: 31.78
UniProt: O00186 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00186 NP_009200.2 592 67764 S587 N K P K D K V S L I K D E _ _
Chimpanzee Pan troglodytes XP_001145368 592 67778 S587 N K P K D K V S L I K D E _ _
Rhesus Macaque Macaca mulatta XP_001087621 798 89892 S793 N K P K D K L S F I K D E _ _
Dog Lupus familis XP_547249 592 67727 S587 N K P K D K V S F T K D E _ _
Cat Felis silvestris
Mouse Mus musculus Q60770 592 67924
Rat Rattus norvegicus P61765 594 67550 D589 L K K L N K T D E E I S S _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508183 589 67400 V579 D F R E F T R V S F E D Q A P
Chicken Gallus gallus Q6R748 594 67454 D589 L K K L N K T D E E I S S _ _
Frog Xenopus laevis NP_001090087 589 67497
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07327 597 67832 S592 I F L S D L G S L S K E D _ _
Honey Bee Apis mellifera XP_396375 585 66573
Nematode Worm Caenorhab. elegans P34815 673 76715 N668 L T N L R D L N K P R D I _ _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SZ77 662 75299 S656 L N E E E E I S L D D I V I _
Baker's Yeast Sacchar. cerevisiae P30619 724 83462 S697 S S P K A A G S L K S E P P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 73 94.7 N.A. 91.8 51.3 N.A. 49.6 51.5 67.5 N.A. N.A. 43.2 44.9 39.6 N.A.
Protein Similarity: 100 100 73.9 96.9 N.A. 96.1 74 N.A. 72.1 73.9 82.7 N.A. N.A. 67 68.9 60.7 N.A.
P-Site Identity: 100 100 84.6 84.6 N.A. 0 15.3 N.A. 6.6 15.3 0 N.A. N.A. 30.7 0 7.6 N.A.
P-Site Similarity: 100 100 92.3 84.6 N.A. 0 23 N.A. 33.3 23 0 N.A. N.A. 46.1 0 30.7 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.3 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 49.4 42.2 N.A.
P-Site Identity: N.A. N.A. N.A. 14.2 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 50 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 36 8 0 15 0 8 8 43 8 0 0 % D
% Glu: 0 0 8 15 8 8 0 0 15 15 8 15 29 0 8 % E
% Phe: 0 15 0 0 8 0 0 0 15 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 22 15 8 8 8 0 % I
% Lys: 0 43 15 36 0 43 0 0 8 8 36 0 0 0 0 % K
% Leu: 29 0 8 22 0 8 15 0 36 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 29 8 8 0 15 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 36 0 0 0 0 0 0 8 0 0 8 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 8 0 8 0 8 0 0 0 8 0 0 0 0 % R
% Ser: 8 8 0 8 0 0 0 50 8 8 8 15 15 0 0 % S
% Thr: 0 8 0 0 0 8 15 0 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 22 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 58 65 % _