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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP3
All Species:
16.67
Human Site:
Y521
Identified Species:
28.21
UniProt:
O00186
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00186
NP_009200.2
592
67764
Y521
R
Q
K
P
R
A
N
Y
L
E
D
R
K
N
G
Chimpanzee
Pan troglodytes
XP_001145368
592
67778
Y521
R
Q
K
P
R
A
N
Y
L
E
D
R
K
N
G
Rhesus Macaque
Macaca mulatta
XP_001087621
798
89892
Y727
R
Q
K
P
R
A
N
Y
L
E
D
R
K
N
G
Dog
Lupus familis
XP_547249
592
67727
Y521
R
Q
K
P
R
T
N
Y
L
E
D
R
K
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q60770
592
67924
L522
Q
K
P
R
T
N
Y
L
E
L
D
R
K
N
G
Rat
Rattus norvegicus
P61765
594
67550
A527
G
H
W
H
K
N
K
A
P
G
E
Y
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
A513
G
H
W
H
K
N
K
A
P
G
E
Y
R
T
G
Chicken
Gallus gallus
Q6R748
594
67454
A527
G
H
W
H
K
N
K
A
P
G
E
Y
R
S
G
Frog
Xenopus laevis
NP_001090087
589
67497
S521
R
Q
K
Q
N
T
I
S
R
D
E
R
K
N
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
H529
P
T
S
A
R
Y
G
H
W
H
K
D
K
G
Q
Honey Bee
Apis mellifera
XP_396375
585
66573
H519
P
T
S
A
R
Y
G
H
W
H
K
D
K
G
S
Nematode Worm
Caenorhab. elegans
P34815
673
76715
E606
R
Y
G
Q
W
H
K
E
R
G
Q
Q
S
N
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
S592
D
S
V
L
G
R
A
S
S
G
F
K
R
K
G
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
N582
A
W
T
T
K
S
S
N
I
K
K
N
I
P
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
73
94.7
N.A.
91.8
51.3
N.A.
49.6
51.5
67.5
N.A.
N.A.
43.2
44.9
39.6
N.A.
Protein Similarity:
100
100
73.9
96.9
N.A.
96.1
74
N.A.
72.1
73.9
82.7
N.A.
N.A.
67
68.9
60.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
33.3
6.6
N.A.
6.6
6.6
40
N.A.
N.A.
13.3
13.3
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
46.6
33.3
N.A.
26.6
33.3
53.3
N.A.
N.A.
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.4
42.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
0
22
8
22
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
8
36
15
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
29
29
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
22
0
8
0
8
0
15
0
0
36
0
0
0
15
65
% G
% His:
0
22
0
22
0
8
0
15
0
15
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% I
% Lys:
0
8
36
0
29
0
29
0
0
8
22
8
58
8
0
% K
% Leu:
0
0
0
8
0
0
0
8
29
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
29
29
8
0
0
0
8
0
50
0
% N
% Pro:
15
0
8
29
0
0
0
0
22
0
0
0
0
8
0
% P
% Gln:
8
36
0
15
0
0
0
0
0
0
8
8
0
0
8
% Q
% Arg:
43
0
0
8
43
8
0
0
15
0
0
43
29
0
8
% R
% Ser:
0
8
15
0
0
8
8
15
8
0
0
0
8
15
8
% S
% Thr:
0
15
8
8
8
15
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
8
22
0
8
0
0
0
15
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
15
8
29
0
0
0
22
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _