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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MASP2
All Species:
3.64
Human Site:
S421
Identified Species:
8.89
UniProt:
O00187
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00187
NP_006601.2
686
75733
S421
A
D
G
F
W
T
S
S
K
G
E
K
S
L
P
Chimpanzee
Pan troglodytes
Q5R1W3
705
80186
T430
E
Q
G
V
Y
T
C
T
A
Q
G
I
W
K
N
Rhesus Macaque
Macaca mulatta
XP_001118815
457
49830
C205
P
P
V
C
E
P
V
C
G
L
S
A
R
T
T
Dog
Lupus familis
XP_850273
728
81731
N422
S
A
Q
G
V
W
M
N
E
V
L
G
R
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91WP0
685
75498
K421
D
G
F
W
T
S
S
K
G
E
K
L
P
P
V
Rat
Rattus norvegicus
Q9JJS8
685
75648
K421
D
G
F
W
T
S
S
K
G
E
K
S
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510548
728
80898
S418
G
A
D
G
F
W
K
S
S
R
G
E
K
S
P
Chicken
Gallus gallus
P25155
475
53123
T223
T
T
T
T
E
S
P
T
P
P
P
R
N
G
S
Frog
Xenopus laevis
NP_001079120
688
77495
I422
A
D
G
F
W
G
D
I
E
S
E
K
T
T
P
Zebra Danio
Brachydanio rerio
NP_001116330
684
76146
I425
I
Q
Q
I
C
L
P
I
C
G
Q
P
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
59.3
42.3
N.A.
81.1
79.4
N.A.
61.2
24.7
50.1
48.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
58.1
63.4
60.1
N.A.
88.4
87.6
N.A.
73.4
39
65.5
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
0
N.A.
6.6
6.6
N.A.
13.3
0
53.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
0
20
N.A.
26.6
26.6
N.A.
26.6
26.6
66.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
0
0
0
0
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
10
10
0
10
10
10
0
0
0
0
0
0
% C
% Asp:
20
20
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
20
0
0
0
20
20
20
10
10
0
0
% E
% Phe:
0
0
20
20
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
30
20
0
10
0
0
30
20
20
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
20
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
20
10
0
20
20
10
10
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
10
10
10
10
20
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
10
% N
% Pro:
10
10
0
0
0
10
20
0
10
10
10
10
10
20
30
% P
% Gln:
0
20
20
0
0
0
0
0
0
10
10
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
10
20
0
0
% R
% Ser:
10
0
0
0
0
30
30
20
10
10
10
10
10
20
10
% S
% Thr:
10
10
10
10
20
20
0
20
0
0
0
0
10
20
10
% T
% Val:
0
0
10
10
10
0
10
0
0
10
0
0
0
0
20
% V
% Trp:
0
0
0
20
20
20
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _