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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4M1
All Species:
25.15
Human Site:
T136
Identified Species:
42.56
UniProt:
O00189
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00189
NP_004713.2
453
49977
T136
M
L
R
N
F
I
Q
T
E
A
V
V
S
K
P
Chimpanzee
Pan troglodytes
XP_001145485
453
49942
T136
M
L
R
N
F
I
Q
T
E
A
V
V
S
K
P
Rhesus Macaque
Macaca mulatta
XP_001101970
453
49960
T136
M
L
R
N
F
I
Q
T
E
A
V
V
S
K
P
Dog
Lupus familis
XP_546965
452
49876
T136
M
L
R
N
F
I
Q
T
E
A
V
V
S
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKC7
449
49491
T136
M
L
R
N
F
I
Q
T
E
A
V
V
S
K
P
Rat
Rattus norvegicus
Q2PWT8
453
49834
T136
M
L
R
N
F
I
Q
T
E
A
A
V
S
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
Q135
A
L
K
T
F
I
T
Q
Q
G
I
K
S
Q
T
Frog
Xenopus laevis
Q801Q8
435
49666
Q135
A
L
K
T
F
I
T
Q
Q
G
I
K
S
Q
H
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
Q135
A
L
K
T
F
I
T
Q
Q
G
I
K
S
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35603
441
50282
Q135
V
L
K
T
F
I
T
Q
Q
G
V
R
T
A
D
Sea Urchin
Strong. purpuratus
XP_782338
436
48883
T136
S
L
K
P
Y
I
Q
T
E
P
V
P
V
K
A
Poplar Tree
Populus trichocarpa
XP_002302340
446
50253
N138
L
L
K
S
Y
V
F
N
E
P
L
V
V
D
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194186
451
50928
N139
V
L
K
S
Y
I
F
N
E
P
I
V
V
S
P
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
Q138
M
L
K
Q
Y
I
T
Q
K
S
F
K
L
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
94.6
N.A.
92.9
92.9
N.A.
N.A.
29.1
29.1
29.3
N.A.
N.A.
N.A.
27.5
39
Protein Similarity:
100
99.7
99.1
96.2
N.A.
95.1
95.1
N.A.
N.A.
50.9
50.7
50.9
N.A.
N.A.
N.A.
49.2
58.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
26.6
26.6
26.6
N.A.
N.A.
N.A.
26.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
53.3
53.3
53.3
N.A.
N.A.
N.A.
53.3
60
Percent
Protein Identity:
35.3
N.A.
N.A.
35.3
24.8
N.A.
Protein Similarity:
60.9
N.A.
N.A.
60
46.9
N.A.
P-Site Identity:
20
N.A.
N.A.
33.3
20
N.A.
P-Site Similarity:
60
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
0
0
0
0
0
43
8
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
72
0
15
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% H
% Ile:
0
0
0
0
0
93
0
0
0
0
29
0
0
0
0
% I
% Lys:
0
0
58
0
0
0
0
0
8
0
0
29
0
50
8
% K
% Leu:
8
100
0
0
0
0
0
0
0
0
8
0
8
0
0
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
43
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
22
0
8
0
0
50
% P
% Gln:
0
0
0
8
0
0
50
36
29
0
0
0
0
22
0
% Q
% Arg:
0
0
43
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
0
15
0
0
0
0
0
8
0
0
65
8
0
% S
% Thr:
0
0
0
29
0
0
36
50
0
0
0
0
8
0
8
% T
% Val:
15
0
0
0
0
8
0
0
0
0
50
58
22
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _