KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4M1
All Species:
23.33
Human Site:
T280
Identified Species:
39.49
UniProt:
O00189
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00189
NP_004713.2
453
49977
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Chimpanzee
Pan troglodytes
XP_001145485
453
49942
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Rhesus Macaque
Macaca mulatta
XP_001101970
453
49960
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Dog
Lupus familis
XP_546965
452
49876
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKC7
449
49491
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Rat
Rattus norvegicus
Q2PWT8
453
49834
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
K279
L
M
R
Y
R
T
T
K
D
I
I
L
P
F
R
Frog
Xenopus laevis
Q801Q8
435
49666
T279
Y
E
L
M
R
Y
R
T
T
K
D
I
I
L
P
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
R279
E
Y
E
L
M
R
Y
R
T
T
K
D
I
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35603
441
50282
M279
P
D
G
E
Y
E
L
M
R
Y
R
T
T
K
D
Sea Urchin
Strong. purpuratus
XP_782338
436
48883
L280
K
Y
G
I
S
N
H
L
S
N
N
L
P
F
Q
Poplar Tree
Populus trichocarpa
XP_002302340
446
50253
V282
P
P
D
G
E
F
P
V
M
N
Y
R
M
T
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194186
451
50928
G283
L
S
L
V
P
P
D
G
E
F
P
V
M
N
Y
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
R282
L
K
F
H
Q
C
V
R
L
S
K
F
E
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
94.6
N.A.
92.9
92.9
N.A.
N.A.
29.1
29.1
29.3
N.A.
N.A.
N.A.
27.5
39
Protein Similarity:
100
99.7
99.1
96.2
N.A.
95.1
95.1
N.A.
N.A.
50.9
50.7
50.9
N.A.
N.A.
N.A.
49.2
58.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
13.3
0
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
13.3
20
N.A.
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
35.3
N.A.
N.A.
35.3
24.8
N.A.
Protein Similarity:
60.9
N.A.
N.A.
60
46.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
8
0
8
0
8
8
0
0
8
% D
% Glu:
8
8
8
8
8
50
0
0
8
0
0
0
8
0
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
8
0
8
0
15
0
% F
% Gly:
0
0
15
8
43
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
8
8
15
8
0
% I
% Lys:
8
8
0
0
0
0
0
8
0
8
15
0
0
8
0
% K
% Leu:
22
0
15
8
0
0
50
8
8
0
0
15
0
50
8
% L
% Met:
0
8
0
8
8
0
0
8
8
43
0
0
15
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
15
8
0
0
15
0
% N
% Pro:
15
50
43
0
8
8
8
0
0
0
8
0
15
0
8
% P
% Gln:
43
0
0
43
8
0
0
0
0
0
0
0
43
0
15
% Q
% Arg:
0
0
8
0
15
8
8
15
8
0
50
8
0
0
8
% R
% Ser:
0
8
0
0
8
0
0
0
8
8
0
0
0
0
43
% S
% Thr:
0
0
0
0
0
8
8
50
15
8
0
8
8
8
0
% T
% Val:
0
0
0
8
0
0
8
8
43
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
15
0
8
8
8
8
0
0
8
8
43
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _