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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB27B
All Species:
52.12
Human Site:
S106
Identified Species:
81.9
UniProt:
O00194
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00194
NP_004154.2
218
24608
S106
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Chimpanzee
Pan troglodytes
XP_523931
218
24620
S106
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Rhesus Macaque
Macaca mulatta
XP_001083017
218
24589
S106
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Dog
Lupus familis
XP_541092
256
28618
S144
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99P58
218
24541
S106
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Rat
Rattus norvegicus
Q99P74
218
24601
S106
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509953
315
35118
S203
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Chicken
Gallus gallus
NP_001162176
221
25048
S106
F
D
L
T
N
E
Q
S
F
L
N
V
R
N
W
Frog
Xenopus laevis
NP_001084598
218
24413
S106
F
D
L
T
S
Q
Q
S
F
L
N
V
R
N
W
Zebra Danio
Brachydanio rerio
NP_001025428
222
25064
S106
F
D
L
T
N
E
Q
S
F
L
N
V
R
N
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
T121
D
W
V
T
Q
I
K
T
Y
S
W
D
N
A
Q
Honey Bee
Apis mellifera
XP_394733
208
24017
Y114
E
Q
L
R
T
H
A
Y
C
E
D
P
D
I
I
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
S109
Y
D
I
T
N
E
E
S
F
N
S
V
Q
D
W
Sea Urchin
Strong. purpuratus
XP_001190480
289
32303
S172
F
D
L
T
N
E
Q
S
F
I
N
I
R
N
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28186
216
23816
H116
W
I
R
N
I
E
Q
H
A
S
D
N
V
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
82.4
N.A.
94.5
93.5
N.A.
64.4
72.8
88
72.9
N.A.
42.7
61.4
42
48.4
Protein Similarity:
100
99.5
99.5
83.5
N.A.
97.7
96.7
N.A.
66.6
84.1
93.5
86.4
N.A.
67.7
77
67.5
61.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
100
86.6
N.A.
6.6
6.6
40
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
33.3
20
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
7
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
80
0
0
0
0
0
0
0
0
14
7
7
7
0
% D
% Glu:
7
0
0
0
0
34
7
0
0
7
0
0
0
0
0
% E
% Phe:
74
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
0
7
7
0
0
0
7
0
7
0
7
7
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
80
0
0
0
0
0
0
67
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
27
0
0
0
0
7
74
7
7
80
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
7
0
0
7
54
80
0
0
0
0
0
7
0
7
% Q
% Arg:
0
0
7
7
0
0
0
0
0
0
0
0
74
0
0
% R
% Ser:
0
0
0
0
54
0
0
80
0
14
7
0
0
0
0
% S
% Thr:
0
0
0
87
7
0
0
7
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
74
7
0
0
% V
% Trp:
7
7
0
0
0
0
0
0
0
0
7
0
0
0
80
% W
% Tyr:
7
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _