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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB27B
All Species:
44.55
Human Site:
Y122
Identified Species:
70
UniProt:
O00194
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00194
NP_004154.2
218
24608
Y122
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Chimpanzee
Pan troglodytes
XP_523931
218
24620
Y122
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Rhesus Macaque
Macaca mulatta
XP_001083017
218
24589
Y122
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Dog
Lupus familis
XP_541092
256
28618
Y160
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99P58
218
24541
Y122
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Rat
Rattus norvegicus
Q99P74
218
24601
Y122
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509953
315
35118
Y219
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Chicken
Gallus gallus
NP_001162176
221
25048
Y122
S
Q
L
Q
M
H
A
Y
C
E
N
P
D
I
V
Frog
Xenopus laevis
NP_001084598
218
24413
Y122
S
Q
L
Q
A
N
A
Y
C
E
N
P
D
I
V
Zebra Danio
Brachydanio rerio
NP_001025428
222
25064
Y122
S
Q
L
Q
T
H
A
Y
C
E
N
P
D
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
D137
I
L
V
G
N
K
C
D
M
E
D
Q
R
V
I
Honey Bee
Apis mellifera
XP_394733
208
24017
E130
C
G
N
K
S
D
L
E
D
K
R
V
V
S
E
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
W125
T
Q
I
K
T
Y
S
W
E
N
A
Q
V
V
L
Sea Urchin
Strong. purpuratus
XP_001190480
289
32303
Y188
T
Q
L
Q
M
H
A
Y
C
E
N
P
D
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28186
216
23816
M132
L
V
G
N
K
A
D
M
D
E
S
K
R
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
82.4
N.A.
94.5
93.5
N.A.
64.4
72.8
88
72.9
N.A.
42.7
61.4
42
48.4
Protein Similarity:
100
99.5
99.5
83.5
N.A.
97.7
96.7
N.A.
66.6
84.1
93.5
86.4
N.A.
67.7
77
67.5
61.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
100
86.6
N.A.
6.6
0
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
33.3
26.6
53.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
54
7
74
0
0
0
7
0
0
7
0
% A
% Cys:
7
0
0
0
0
0
7
0
74
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
7
14
0
7
0
74
0
0
% D
% Glu:
0
0
0
0
0
0
0
7
7
87
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
0
0
0
0
67
7
% I
% Lys:
0
0
0
14
7
7
0
0
0
7
0
7
0
0
0
% K
% Leu:
7
7
74
0
0
0
7
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
14
0
0
7
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
54
0
0
0
7
74
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
74
0
0
0
% P
% Gln:
0
80
0
74
0
0
0
0
0
0
0
14
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
14
0
0
% R
% Ser:
67
0
0
0
7
0
7
0
0
0
7
0
0
7
0
% S
% Thr:
14
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
7
0
0
0
0
0
0
0
0
7
14
20
80
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _