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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB27B
All Species:
36.97
Human Site:
Y53
Identified Species:
58.1
UniProt:
O00194
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00194
NP_004154.2
218
24608
Y53
F
R
E
K
R
V
V
Y
N
A
Q
G
P
N
G
Chimpanzee
Pan troglodytes
XP_523931
218
24620
Y53
F
R
E
K
R
V
V
Y
N
A
Q
G
P
N
G
Rhesus Macaque
Macaca mulatta
XP_001083017
218
24589
Y53
F
R
E
K
R
V
V
Y
N
A
Q
G
P
N
G
Dog
Lupus familis
XP_541092
256
28618
Y91
F
R
E
K
R
V
V
Y
N
T
Q
G
P
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99P58
218
24541
Y53
F
R
E
K
R
V
V
Y
D
T
Q
G
A
D
G
Rat
Rattus norvegicus
Q99P74
218
24601
Y53
F
R
E
K
R
V
V
Y
D
T
Q
G
A
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509953
315
35118
Y150
F
R
E
K
R
V
V
Y
N
S
R
G
P
N
G
Chicken
Gallus gallus
NP_001162176
221
25048
Y53
F
R
E
K
R
V
V
Y
R
P
N
G
P
D
G
Frog
Xenopus laevis
NP_001084598
218
24413
Y53
F
R
E
K
R
V
I
Y
S
N
A
G
P
G
G
Zebra Danio
Brachydanio rerio
NP_001025428
222
25064
Y53
F
R
E
K
R
V
V
Y
K
S
S
G
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25228
220
24843
R65
F
K
V
K
T
V
F
R
H
D
K
R
V
K
L
Honey Bee
Apis mellifera
XP_394733
208
24017
L62
G
R
T
Q
R
V
H
L
Q
L
W
D
T
A
G
Nematode Worm
Caenorhab. elegans
Q94986
219
24741
G56
S
A
F
V
S
T
V
G
I
D
F
K
V
K
T
Sea Urchin
Strong. purpuratus
XP_001190480
289
32303
H120
F
R
E
K
R
V
T
H
R
P
K
G
A
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28186
216
23816
L59
F
K
I
R
T
I
E
L
D
G
K
R
I
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
82.4
N.A.
94.5
93.5
N.A.
64.4
72.8
88
72.9
N.A.
42.7
61.4
42
48.4
Protein Similarity:
100
99.5
99.5
83.5
N.A.
97.7
96.7
N.A.
66.6
84.1
93.5
86.4
N.A.
67.7
77
67.5
61.9
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
86.6
73.3
66.6
73.3
N.A.
20
26.6
6.6
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
100
80
80
86.6
N.A.
40
33.3
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
20
7
0
20
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
20
14
0
7
0
34
0
% D
% Glu:
0
0
74
0
0
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
87
0
7
0
0
0
7
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
7
0
7
0
74
0
7
74
% G
% His:
0
0
0
0
0
0
7
7
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
7
7
0
7
0
0
0
7
0
0
% I
% Lys:
0
14
0
80
0
0
0
0
7
0
20
7
0
20
0
% K
% Leu:
0
0
0
0
0
0
0
14
0
7
0
0
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
34
7
7
0
0
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
14
0
0
54
0
7
% P
% Gln:
0
0
0
7
0
0
0
0
7
0
40
0
0
0
0
% Q
% Arg:
0
80
0
7
80
0
0
7
14
0
7
14
0
0
0
% R
% Ser:
7
0
0
0
7
0
0
0
7
14
7
0
0
0
0
% S
% Thr:
0
0
7
0
14
7
7
0
0
20
0
0
7
0
7
% T
% Val:
0
0
7
7
0
87
67
0
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _